Rhipicephalus sanguineus ticks are significant for both medical and veterinary fields due to their feeding process and the pathogens they transmit through their saliva.
A study was conducted on male Wistar rat liver cells after administering different treatments, including salivary gland extract from these ticks, to understand their effects on liver tissue.
The findings revealed moderate alterations in the liver caused by both the salivary gland extract and phosphate buffer saline, such as lipid plaques, cytoplasmic vacuolation, and changes in nuclear structure, although no severe disorganization of the liver tissue was observed.