Use of Epilobium parviflorum in the Treatment of Benign Prostatic Hyperplasia in Canines.

The objective of the study was to evaluate the effect of Epilobium parviflorum (EP) as a treatment for benign prostatic hyperplasia (BPH) in dogs based on two clinical case reports. Two dogs with BPH were treated for 2 months with EP extract. For both cases, follow-up was performed with B-mode ultrasound on Days 7, 15, 30 and 60 after starting treatment, and measurements of the length, width and height of the prostate were taken to calculate its volume (cm).

Functional ultrasound and brain connectivity reveal central nervous system compromise in Trembler-J mice model of Charcot-Marie-Tooth disease.

The Charcot-Marie-Tooth-1E (CMT1E) disease is typically described as a peripheral neuropathy in humans, causing decreased nerve conduction, spastic paralysis, and tremor. The Trembler-J (TrJ) mice serve as a high fidelity model of this disease. Here, we use functional ultrasound (fUS) and functional connectivity (FC) to analyze TrJ mice's brain activity during sensory stimulation and resting state experiments against wild type (WT) mice - the healthy counterpart.

Epidemiology of cat bites to people in Uruguay: Effects of the age and sex of the victim, season of the year, and the COVID-19 pandemic.

Background: Cat bites to people are an important public health problem. However, very little information exists on the epidemiology of people bitten by cats at the level of an entire country in Latin America. Additionally, the COVID-19 pandemic significantly influenced people's lives and their relationships with pets, which could potentially affect the frequency of people bitten by cats.

Identification of Candidate Genes and Pathways Linked to the Temperament Trait in Sheep.

Temperament can be defined as the emotional variability among animals of the same species in response to the same stimulus, grouping animals by their reactivity as nervous, intermediate, or calm. Our goal was to identify genomic regions with the temperament phenotype measured by the Isolation Box Test (IBT) by single-step genome-wide association studies (ssGWAS). The database consisted of 4317 animals with temperament records, and 1697 genotyped animals with 38,268 effective Single Nucleotide Polymorphism (SNP) after quality control.

Sexual behaviour of young rams is improved and less stressful after intranasal administration of oxytocin.

The aim of this study was to determine if intranasal administration of oxytocin modifies sexual behaviour and the stress response in young rams during sexual tests with ewes in oestrus. Ten rams were used in a cross-over design. At Day 0, the control group (CG, n = 5) received isotonic saline spray intranasally, and the treated group (OTG, n = 5) received oxytocin (24 IU) intranasally, 40 min before the sexual test.

Clinical signs associated with prostatic disorders in canines: Retrospective study in Uruguay (2011-2019).

Background: Prostate disease represents about 0.7% of diseases in canines. The main diagnosed pathology is benign prostatic hyperplasia (BPH).

In Vivo Ultrafast Doppler Imaging Combined with Confocal Microscopy and Behavioral Approaches to Gain Insight into the Central Expression of Peripheral Neuropathy in Trembler-J Mice.

The main human hereditary peripheral neuropathy (Charcot-Marie-Tooth, CMT), manifests in progressive sensory and motor deficits. Mutations in the compact myelin protein gene pmp22 cause more than 50% of all CMTs. CMT1E is a subtype of CMT1 myelinopathy carrying micro-mutations in pmp22.

Epidemiology of dog bites to people in Uruguay (2010-2020).

Background: Dog bites to people are a serious public health problem. Limited information exists at the country level in Latin America. The COVID-19 pandemic changed people's lifestyles and their relationship with pets, and this could potentially affect the incidence of dog bites injuries.

The environment matters: season and female contact affect the behavior of captive male antelope.

The addax antelope () is a species under serious threat of extinction, as it is more abundant in captivity than in the wild. However, little is known about its basic biology. The aims of this study were to determine how locomotor, feeding, aggressive, marking, and sexual behavior of male addax allocated in all-male groups vary with season and with female contact (i.

Characterization of Raid Hipico Uruguayo Competencies by Ride Type: Causes of Death and Risk Factors.

RHU is the oldest endurance sport in Uruguay. However, despite 80 years of racing, there are no studies to characterize this type of competition, explore rates and causes of death, and identify the associated risk factors. The aim was to characterize the Raid Hipico Uruguayo (RHU) competencies according to the distance (short (SR, 60 km) vs.

Udder Hygiene and Mastitis Indicators in Contrasting Environmental Conditions during Half-Time Confinement in Pasture-Based Dairy Systems.

This study aimed to compare the association between two types of housing, compost barns (CB) vs. outdoor soil-bedded yard (OD), and udder hygiene and mastitis indicators in Holstein dairy cows calving in autumn ( = 31) and spring ( = 27). After calving, cows were transferred to a pasture-based system with half-time confinement in one of two treatments: CB or OD.

Different Conditions during Confinement in Pasture-Based Systems and Feeding Systems Affect the Fatty Acid Profile in the Milk and Cheese of Holstein Dairy Cows.

The diet of dairy cows influences the fatty acid (FA) profiles of their milk and cheese, but how these are affected by different conditions during confinement in a mixed system (MS:grazing + total mixed ration:TMR) is not known. The aim of this study was to compare the FAs of the milk and cheese from MS in a compost-bedded pack barns (CB-GRZ) versus an outdoor soil-bedded pen (OD-GRZ) during confinement, and with a confinement system (100%TMR) in a compost-bedded pack barns (CB-TMR). Individual milk samples ( = 12 cows/group), cheese, and pooled milk (MilkP) samples were collected.

Dairy Cows' Temperament and Milking Performance during the Adaptation to an Automatic Milking System.

Adaptative responses of cows to an automatic milking system (AMS) could depend on their temperament, i.e., cows with certain temperament profiles could be able to cope more successfully with the AMS.

CaMKIV/CREB/BDNF signaling pathway expression in prefrontal cortex, amygdala, hippocampus and hypothalamus in streptozotocin-induced diabetic mice with anxious-like behavior.

Individuals with diabetes mellitus (DM) tend to manifest anxiety and depression, which could be related to changes in the expression of calcium/calmodulin-dependent protein kinase IV (CaMKIV), transcription factor cyclic AMP-responsive element binding protein (CREB), phosphorylated CREB (pCREB) and brain-derived neurotrophic factor (BDNF) in different brain regions. The objective of this study was to determine whether mice with type 1 diabetes (T1DM) induced with streptozotocin show a profile of anxious-type behaviors and alterations in the expression/activity of CaMKIV, CREB, pCREB and BDNF in different regions of the brain (prefrontal cortex, amygdala, hippocampus and hypothalamus) in comparison to non-diabetic mice (NDB). Mice with 3 months of chronic DM showed an anxious-like behavioral profile in two anxiety tests (Open Field and Elevated Plus Maze), when compared to NDB.

Intensity distribution segmentation in ultrafast Doppler combined with scanning laser confocal microscopy for assessing vascular changes associated with ageing in murine hippocampi.

The hippocampus plays an important role in learning and memory, requiring high-neuronal oxygenation. Understanding the relationship between blood flow and vascular structure-and how it changes with ageing-is physiologically and anatomically relevant. Ultrafast Doppler ([Formula: see text]Doppler) and scanning laser confocal microscopy (SLCM) are powerful imaging modalities that can measure in vivo cerebral blood volume (CBV) and post mortem vascular structure, respectively.

Post-castration prostatic involution: A morphometric and endocrine study of healthy canines and those with benign prostatic hyperplasia.

The objective of this study was to evaluate the effect of castration on dimensions of the prostate by B-mode ultrasound for 90 days, as well as to evaluate changes in serum concentrations of testosterone and oestradiol in clinically healthy canines and those with benign prostatic hyperplasia (BPH). Three groups of animals were used: healthy canines castrated on day 0 (HCC, n = 8), canines with a diagnosis of benign prostatic hyperplasia (BPHC, n = 9) castrated on day 0 and healthy uncastrated canines (IHCC, n = 10). Prostate size was obtained by B-mode ultrasound, while blood samples were collected (days 0, 7, 14, 28, 60 and 90 post-castration) to determine the serum testosterone and oestradiol concentration.

Intranasal oxytocin affects the stress response to social isolation in sheep.

Oxytocin (OT) is a neuropeptide hormone that modulates several social behaviors and can affect the anxiety and stress response. The aim of this study was to determine if administration of intranasal OT affects the stress response to social isolation in sheep. Twenty adult Merino ewes were assigned to two groups; 1) Control group (CG, n = 10), which received an intranasal administration of isotonic saline and 2) Oxytocin-treated group (OTG, n = 10), which received an intranasal administration of OT (24 IU) 40 min before the animals were placed in the social isolation test.

Growth of foetal bones and metabolic profile during gestation in primiparous ewes and multiparous ewes.

Primiparous ewes and multiparous ewes show physiological differences during pregnancy, which can have an impact on the development of their offspring. The objective of this study was to compare the changes in the metabolic profile and in the size of some foetal bones throughout gestation between primiparous and multiparous ewes. Twelve primiparous (PM) ewes and 14 multiparous (MT) ewes were used.

Do dogs rescue their owners from a stressful situation? A behavioral and physiological assessment.

Rescue behavior is considered a type of pro-social response, defined as a voluntary action directed to benefit another individual who is in a stressful or dangerous situation. In two experiments, we investigated whether dogs would rescue their owners when the person was trapped inside a wooden box and emitted clear signs of stress. The performance of these dogs was compared against that of a control group in which the owners remained calm while trapped.

Serial collection method of dog saliva: Effects of different chemical stimulants on behaviour, volume and saliva composition.

The objective of this study was to evaluate different chemical stimulants with different flavours such as acids (citric and acetic), sweet (sucrose) and salty (sodium chloride) applied to cotton rolls and compare their effects on the volume, pH and protein concentrations of the saliva collected and the behaviour of dogs during sampling management. As an additional objective, serum cortisol concentrations of saliva samples obtained with or without citric acid and with or without previous pH adjustment were compared. Five clinically healthy were randomly assigned to one of 5 treatments with cottons with different substances: 1) control, 2) citric acid, 3) acetic acid, 4) sodium chloride, 5) sucrose.

Sperm collection by transrectal ultrasound-guided massage of the accessory sex glands is less stressful than electroejaculation without altering sperm characteristics in conscious goat bucks.

In anesthetized non-domestic ruminants transrectal ultrasound-guided massage of the accessory sex glands (TUMASG) is an alternative method to collect semen slightly less stressful than electroejaculation (EE). However, some sperm characteristics are better when semen is collected with EE than with TUMASG. As anesthesia reduces the response to stressors, the advantages of TUMASG may be reduced in anesthetized animals, and thus, TUMASG may be even more advantageous in conscious animals.