Publications by authors named "Juan P Paviolo"

Article Synopsis
  • Susac syndrome, multiple sclerosis, and primary angiitis of the central nervous system often present similar symptoms, making accurate diagnosis a challenge; the study aimed to improve this through a new scoring system called the SPAMS score.
  • The research involved 99 patients from South America and utilized an elastic-net model to determine important MRI features for distinguishing between these conditions.
  • The SPAMS score demonstrated high diagnostic accuracy, effectively differentiating SuS from MS and PACNS, highlighting the importance of specific MRI findings for timely interventions and potentially better patient outcomes.
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Rapidly progressive dementias are conditions of impairment in more than one cognitive domain with functional compromise that progress in less than 1 to 2 years; and neurosyphilis is one of the etiologies. Syphilis is a chronic bacterial infection that causes a series of highly variable clinical conditions during the first 2 to 3 years, followed by a prolonged latent stage that can progress to a tertiary infection stage. After a period of years, or even decades, a third of people with untreated latent syphilis will have clinical manifestations of tertiary syphilis such as neurosyphilis.

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Susac syndrome is a rare disorder caused by autoimmune-mediated occlusions of microvessels in the brain, retina and inner ear. These occlusions lead to a characteristic clinical triad of central nervous system dysfunction, visual disturbances and vestibule-cochlear deficits. The diagnosis is based on clinical manifestations and complementary studies, which demonstrate the involvement of three systems.

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Objective: To describe the clinical features, etiology, findings from neuroimaging, and treatment results in a series of 29 patients with Holmes tremor (HT).

Methods: A retrospective study was performed based on review of medical records and videos of patients with HT diagnosis.

Results: A total of 16 women and 13 men were included.

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Unlabelled: Writing tremor (WT) is a task-specific tremor that occurs only or mostly while writing with the dominant hand. Secondary cases are extremely uncommon. We report on a patient who, after developing a WT after an ischemic stroke, had a remarkable response to topiramate (TPM).

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