Association between major dietary patterns and obesity phenotypes in southwest China: baseline survey results from Hechuan.

Background: This study aimed to identify the main dietary patterns in Hechuan and clarify how they are associated with obesity phenotypes.

Methods: A cross-sectional study was conducted based on a baseline survey of a general population cohort study in southwest China. A semi-quantitative food frequency questionnaire (FFQ) was used to investigate the dietary habits of the participants in the past year.

Connecting genomic and proteomic signatures of amyloid burden in the brain.

Background: Alzheimer's disease (AD) has a high heritable component characteristic of complex diseases, yet many of the genetic risk factors remain unknown. We combined genome-wide association studies (GWAS) on amyloid endophenotypes measured in cerebrospinal fluid (CSF) and positron emission tomography (PET) as surrogates of amyloid pathology, which may be helpful to understand the underlying biology of the disease.

Methods: We performed a meta-analysis of GWAS of CSF Aβ42 and PET measures combining six independent cohorts (n=2,076).

Involving a Dedicated Epidural-Caring Nurse in Labor Ward Practice Improves Maternal Satisfaction towards Childbirth: A Retrospective Study.

The quality of healthcare is crucially linked to patient satisfaction, particularly in the provision of neuraxial analgesia for labor pain. Neuraxial analgesia for labor pain control should ideally be readily available when requested. However, in real-world practice, anesthesiologists may not always respond immediately to maternal demands, which can compromise the quality of care.

Bayesian and network models with covariate effects for predicting heating energy demand.

The spatial effect is an element presented in many geostatistical works and it should be incorporated into studies regarding the heating energy demand of residential building stocks. The most common approaches have been made by simple descriptive statistics or using analyses by Markov random fields. In this work, we propose two different methods.

A multiple phenotype imputation method for genetic diversity and core collection in Taiwanese vegetable soybean.

Establishment of vegetable soybean (edamame) [ (L.) Merr.] germplasms has been highly valued in Asia and the United States owing to the increasing market demand for edamame.

Spatio-temporal modeling of traffic accidents incidence on urban road networks based on an explicit network triangulation.

Traffic deaths and injuries are one of the major global public health concerns. The present study considers accident records in an urban environment to explore and analyze spatial and temporal in the incidence of road traffic accidents. We propose a spatio-temporal model to provide predictions of the number of traffic collisions on any given road segment, to further generate a risk map of the entire road network.

Ketamine for resistant depression: a scoping review.

Ketamine is a fast-acting anesthetic with hypnotic properties. Moreover, could potentially improve affective symptoms in patients with refractory depressive disorder. Objective.

New insights into the genetic etiology of Alzheimer's disease and related dementias.

Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis.

Role of laparoscopy in the immediate, intermediate, and long-term management of iatrogenic bile duct injuries during laparoscopic cholecystectomy.

Purpose: Bile duct injuries (BDI) during a laparoscopic cholecystectomy still remain as one of the most feared complications in surgery. The use of laparoscopy for its management is a controversial subject of discussion. The purpose of this study is to assess the amount of possibilities that a laparoscopic approach allows in its resolution.

Multidisciplinary Approach for Full-Mouth Rehabilitation of a Young Adult Patient with Ameloblastoma.

Ameloblastoma is a benign but locally invasive neoplasm of the odontogenic epithelium that tends to grow slowly in the mandible or maxilla. It can be highly destructive to the surrounding dental anatomy and can cause death by progressive spread to nearby vital structures in rare cases. Marginal resection is the most effective method of eliminating the tumor, but treatment can further contribute to oral and dental deformity and malfunction.

Data on CO, temperature and air humidity records in Spanish classrooms during the reopening of schools in the COVID-19 pandemic.

In order to reduce the advance of the pandemic produced by COVID-19, many actions and restrictions have been applied and the field of education has been no exception. In Spain, during the academic year 2020-2021, face-to-face teaching generally continued in both primary and secondary schools. Throughout the year, different measures have been taken to reduce the likelihood of contagion in classrooms, one of which was to improve ventilation by opening windows and doors.

Continuous polymerase chain reaction microfluidics integrated with a gold-capped nanoslit sensing chip for Epstein-Barr virus detection.

We present the first combination of a microfluidic polymerase chain reaction (PCR) with a gold nanoslit-based surface plasmon resonance (SPR) sensor for detecting the DNA sequence of latent membrane protein 1 (LMP1). The PCR microchannel was produced through a laser scribing technique, and the SPR nanoslit chip was manufactured via hot-embossing nanoimprinting lithography. Afterward, the LMP1 DNA probe was adsorbed onto the SPR chip of the integrated device through electrostatic interactions for further detection.

Bioactivity and Bone Cell Formation with Poly-ε-Caprolactone/Bioceramic 3D Porous Scaffolds.

This study applied poly-ε-caprolactone (PCL), a biomedical ceramic powder as an additive (nano-hydroxyapatite (nHA) or β-tricalcium diphosphate (β-TCP)), and sodium chloride (NaCl) and ammonium bicarbonate ((NH)HCO) as porogens; these stuffs were used as scaffold materials. An improved solvent-casting/particulate-leaching method was utilized to fabricate 3D porous scaffolds. In this study we examined the physical properties (elastic modulus, porosity, and contact angle) and degradation properties (weight loss and pH value) of the 3D porous scaffolds.

Non-Invasive Cattle Body Temperature Measurement Using Infrared Thermography and Auxiliary Sensors.

To achieve a sensitive and accurate method in body temperature measurement of cattle, this study explores the uses of infrared thermography (IRT), an anemometer, and a humiture meter as a multiple sensors architecture. The influence of environmental factors on IRT, such as wind speed, ambient temperature, and humidity, was considered. The proposed signal processes removed the IRT frames affected by air flow, and also eliminated the IRT frames affected by random body movement of cattle using the frame difference method.

Association between the New COVID-19 Cases and Air Pollution with Meteorological Elements in Nine Counties of New York State.

The principal objective of this article is to assess the possible association between the number of COVID-19 infected cases and the concentrations of fine particulate matter (PM) and ozone (O), atmospheric pollutants related to people's mobility in urban areas, taking also into account the effect of meteorological conditions. We fit a generalized linear mixed model which includes spatial and temporal terms in order to detect the effect of the meteorological elements and COVID-19 infected cases on the pollutant concentrations. We consider nine counties of the state of New York which registered the highest number of COVID-19 infected cases.

Reliability Evaluation of the Data Acquisition Potential of a Low-Cost Climatic Network for Applications in Agriculture.

Temperature, humidity and precipitation have a strong influence on the generation of diseases in different crops, especially in vine. In recent years, advances in different disciplines have enabled the deployment of sensor nodes on agricultural plots. These sensors are characterised by a low cost and so the reliability of the data obtained from them can be compromised, as they are built from low-confidence components.

Transposon Insertion Sequencing in a Clinical Isolate of Legionella pneumophila Identifies Essential Genes and Determinants of Natural Transformation.

is a Gram-negative bacterium ubiquitous in freshwater environments which, if inhaled, can cause a severe pneumonia in humans. The emergence of is linked to several traits selected in the environment, the acquisition of some of which involved intra- and interkingdom horizontal gene transfer events. Transposon insertion sequencing (TIS) is a powerful method to identify the genetic basis of selectable traits as well as to identify fitness determinants and essential genes, which are possible antibiotic targets.

Microsatellite instability in Costa Rican patients with colorectal adenocarcinoma and its association with overall survival and response to fluoropyrimidine-based chemotherapy.

Background: Microsatellite instability (MSI) is a prognostic and predictive factor in colorectal cancer (CRC). Previous trials have acknowledged that MSI prevalence varies according to ethnicity. The aim of this study was to determine the prevalence of MSI among CRC patients from Costa Rica and to analyze its influence on overall survival (OS) and response to fluoropyrimidine-based chemotherapy.

LMP1 gene detection using a capped gold nanowire array surface plasmon resonance sensor in a microfluidic chip.

Surface plasmon resonance (SPR) nanowire array chips with a microfluidic system are an effective detection method for a rapid test device. This study investigated a capped gold nanowire array and a microfluidic test platform to provide a fundamental understanding of the kinetic binding of SPR nanowires and the surface gold refractive index. The device sensitivity of the SPR nanowire array was 485 nm RIU-1 and the detection limit was 4.

Diverse conjugative elements silence natural transformation in species.

Natural transformation (i.e., the uptake of DNA and its stable integration in the chromosome) is a major mechanism of horizontal gene transfer in bacteria.

The economic cost of dementia: A systematic review.

The purpose of this article is to analyse the available literature describing the economic burden of dementia and to compare costs between studies examining cost drivers. To shed light on this field, a systematic review is performed using PubMed, the Cochrane Library and Web of Science. An eight-year retrospective horizon was considered until 25 May 2018.