Stress During Pregnancy and the Development of Diseases in the offspring: A Systematic-Review and Meta-Analysis.

Objective: The goal of this systematic-review and meta-analysis was to assess whether high maternal stress during pregnancy is associated with the development of pediatric pathology.

Design: Epidemiological peer-reviewed studies published in English or Spanish assessing associations between maternal stress during pregnancy and psychiatric and medical diseases were selected.

Participants: We retrieved 73,024 citations; 42 studies meeting inclusion criteria were assessed.