Caerulines A and B, Flavonol Diacylglycosides from .

Two undescribed 4'--methylkaempferol-[3″,4″-di--coumaroyl]-α-l-rhamnopyranosides, caerulines A and B (), along with three known 4'--methylkaempferol diacylrhamnosides isomers () were isolated from an ethanol extract of the leaves of , a native plant growing on the Colombian Caribbean coast. The chemical structures of and were elucidated by spectroscopic methods. The effect of compounds against four pathogenic microorganisms [i.

Chemical and Antifungal Variability of Several Accessions of A. Juss. from Six Locations Across the Colombian Caribbean Coast: Identification of Antifungal Azadirone Limonoids.

Plant materials (i.e., leaves, fruits, and seeds) from 40 trees of A.

Bio-Guided Fractionation of Ethanol Extract of Leaves of Kunt (Rutaceae) Led to the Isolation of Two Cytotoxic Quinoline Alkaloids: Evidence of Selectivity Against Leukemia Cells.

Bio-guided fractionation performed on the leaves-derived ethanol extract of (Rutaceae), a plant used in traditional medicine, led to the isolation of two alkaloids, kokusaginine and flindersiamine , as main cytotoxic agents. Primary ethanolic extract and raw fractions exhibited cell inhibition against five cancer cell lines at different levels (25-97% inhibition at 50 µg/mL) as well as isolated alkaloids - (30-90% inhibition at 20 µM). Although alkaloid generally was the most active compound, both alkaloids showed a selective effect on K562, a human chronic myelogenous leukemia cell line.