Publications by authors named "Juan M Ruiz Nodar"

Aims: Evidence regarding the safety of early discharge following transcatheter aortic valve implantation (TAVI) is limited. The aim of this study was to evaluate the safety of very early (<24) and early discharge (24-48 h) as compared to standard discharge (>48 h), supported by the implementation of a voice-based virtual assistant using artificial intelligence (AI) and natural language processing.

Methods And Results: Single-arm prospective observational study that included consecutive patients who underwent TAVI in a tertiary hospital in 2023 and were discharged under an AI follow-up programme.

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Article Synopsis
  • The article reviews the 2023 activity report from the Interventional Cardiology Association of the Spanish Society of Cardiology, highlighting key trends in interventional cardiology practices in Spain.
  • A survey involving 119 hospitals revealed a slight decrease in diagnostic studies but an increase in percutaneous coronary interventions (PCI), with a notable rise in the use of drug-coated balloons and techniques for plaque modification.
  • The findings indicate a stabilization in coronary interventions while showcasing a growth in complex procedures, particularly for valvular and nonvalvular structural heart diseases, with primary PCI becoming the leading treatment for myocardial infarction.
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Current cardiovascular prevention guidelines emphasise considering sex, gender, and gender identity in risk assessment. This study evaluated the impact of lifestyle habits and chronic diseases on cardiovascular mortality risk in women over 50 with high vascular risk and developed a predictive model for menopausal women with cardiovascular risk factors. A retrospective cohort study used data from the 2011 Spanish National Health Survey and the national death register, focusing on menopausal and postmenopausal women without prior cardiovascular events but with at least one major risk factor.

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  • Antithrombotic treatment (ATT) after left atrial appendage occlusion (LAAO) is debated, especially for patients at high bleeding risk.
  • This study compared simplified ATT, which involves single antiplatelet or no treatment, to conventional ATT, including dual antiplatelet or anticoagulation therapy, in very high bleeding risk patients.
  • Results showed no significant differences in major adverse outcomes between the two treatment groups; however, patients with a history of major bleeding had a lower incidence of major bleeding with the simplified ATT.
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Objectives: This study aims to assess the current state of childhood overweight and obesity in Spain, and its relationship with socioeconomic status and health-related behaviors.

Methods: Population-based cross-sectional observational study, based on the 2017 National Health Survey in minors in Spain. This study included all children surveyed who were aged 1-14 years.

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Background And Aims: Cardiovascular risk increases during menopause, so the medical and scientific community should consider women's specific risk factors to prevent cardiovascular disease. This study aims to assess the risk factors for the incidence of major adverse cardiovascular events (MACE) exclusive to postmenopausal women.

Methods: We conducted a prospective cohort study in postmenopausal women aged 40 years and older, who were included in the UK Biobank cohort between 2006 and 2010 and followed to 2021 (12 years).

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  • This article reports on the annual activities of the Interventional Cardiology Association of the Spanish Society of Cardiology for 2022.
  • A total of 111 centers participated, revealing a 4.8% increase in diagnostic studies and a significant 22% rise in PCIs on the left main coronary artery, while the overall PCI numbers remained stable.
  • Key trends included a preference for the radial approach in 94.9% of cases, increased use of drug-eluting balloons and intracoronary imaging, and a continuous rise in noncoronary procedures, especially those related to heart valve and structural heart issues.
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  • * This study followed patients with NSTEACS using hsTn tests for two years to see if these tests influence medium-term health outcomes like heart-related events, bleeding, and overall mortality.
  • * Results showed no significant differences in major cardiovascular events between UA and NSTEMI patients, but NSTEMI patients experienced higher cardiovascular and overall mortality rates at the two-year mark.
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Based on the latest knowledge and technological advancements, it is still debatable whether a modern revascularisation approach in the setting of acute myocardial infarction (AMI), including complete revascularisation (in patients with significant non-culprit lesions) with newer-generation highly biocompatible drug-eluting stents, requires prolonged dual antiplatelet therapy (DAPT). TARGET-FIRST (ClinicalTrials.gov: NCT04753749) is a prospective, open-label, multicentre, randomised controlled study comparing short (one month) DAPT versus standard (12 months) DAPT in a population of patients with non-ST/ST-segment elevation myocardial infarction, completely revascularised at index or staged procedure (within 7 days), using Firehawk, an abluminal in-groove biodegradable polymer rapamycin-eluting stent.

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  • Coronary intravascular lithotripsy (IVL) is a new method used to fix problems when stents don’t expand properly in the heart.
  • A patient had a very bad case of stent underexpansion, but after two sessions of IVL treatment, the problem was fixed, and there was no damage to the stent after a year.
  • However, they found a serious issue in a different area that had been overlooked before, which might have led to new blockages, showing that more treatment might be needed for stubborn cases.
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Introduction And Objectives: Transthyretin cardiac amyloidosis (ATTR-CA) patients often have atrial fibrillation and increased bleeding/thrombogenic risks. We aimed to evaluate outcomes of left atrial appendage closure (LAAC) compared with patients without a known diagnosis of CA.

Methods: Comparison at long-term of patients diagnosed with ATTR-CA who underwent LAAC between 2009 and 2020 and those without a known diagnosis of CA.

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The treatment of acute coronary syndrome (ACS) in elderly patients continues to be a challenge because of the characteS.G.B.

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  • The study examined the effects of diabetes mellitus (DM) on patients with acute coronary syndrome (ACS) and their 2-year health outcomes based on the type of antiplatelet therapy used.
  • Among the 1717 ACS patients, 38% had DM, and these patients were older, more often female, and had more health complications, with clopidogrel being the most prescribed medication.
  • Findings indicated that DM significantly increased the risk of major adverse cardiovascular events (MACEs) and overall mortality, with the use of ticagrelor or prasugrel linked to better outcomes compared to clopidogrel in diabetic patients.
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Background: The Watchman FLX is a device upgrade of the Watchman 2.5 that incorporates several design enhancements intended to simplify left atrial appendage occlusion (LAAO) and improve procedural outcomes. This study compares -procedural results of LAAO with Watchman FLX (Boston Scientific, Marlborough, Massachusetts) in centers with varying degrees of experience with the Watchman 2.

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Introduction And Objectives: There are models for cardiovascular risk prediction in the general population, but the prediction of risk in postmenopausal women has not been specifically studied. This study aimed to determine the association of lifestyle habits and chronic diseases with cardiovascular risk in menopausal women, as well as to build a risk scale.

Methods: Retrospective population-based cohort study using data from the 2011 National Health Survey of Spain as a data source, Women ≥ 50 years were included.

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Objective: Left atrial appendage (LAA) thrombus has heretofore been considered a contraindication to percutaneous LAA closure (LAAC). Data regarding its management are very limited. The aim of this study was to analyse the medical and invasive treatment of patients referred for LAAC in the presence of LAA thrombus.

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Few studies have addressed to date the interaction between sex and diabetes mellitus (DM) in the prognosis of elderly patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). Our aim was to address the role of DM in the prognosis of non-selected elderly patients with NSTEACS according to sex. A retrospective analysis from 11 Spanish NSTEACS registries was conducted, including patients aged ≥70 years.

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Background: It is estimated that 5% to 10% of patients with myocardial infarction (MI) present with no obstructive coronary artery lesions. Until now, most studies have focused on acute coronary syndrome, including different clinical entities with a similar presentation encompassed under the term MINOCA (MI with non-obstructive coronary arteries). The aim of this study is to assess the prognosis of patients diagnosed with true infarction, confirmed by cardiovascular magnetic resonance (CMR), in the absence of significant coronary lesions.

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Background: Clinical trials have assessed the effect of direct oral antagonists (DOACs) in patients with atrial fibrillation (AF) after percutaneous coronary interventions (PCI). Studies were designed to test the effect on bleeding incidence, but concerns related to safety on ischemic events remain.

Methods: We performed a meta-analysis with currently available studies involving DOACs versus Vitamin-K antagonist (VKA) in patients with AF after PCI.

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Article Synopsis
  • The study aimed to assess how comorbidities impact the effectiveness of in-hospital revascularization in older patients with non-ST-segment elevation acute coronary syndrome (NSTEACS).
  • Researchers analyzed data from 7211 patients aged 70 and older, finding that revascularization significantly reduced 1-year mortality rates, although this benefit diminished as comorbidities increased.
  • Specifically, patients with renal failure, peripheral artery disease, and chronic pulmonary disease experienced fewer benefits from revascularization compared to those with fewer comorbidities, while diabetes and previous strokes did not significantly alter the results.
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