Publications by authors named "Juan M Martinez-Villalobos"

Vibrio diabolicus is widely distributed in the marine environment and is an important pathogen of aquatic organisms such as shrimp, fish, and mollusks. The emergence of multi-drug resistance among these bacteria has resulted in a global public health problem, which requires alternative treatment approaches, such as phage therapy. In the present study, we isolated the phage vB_Vc_SrVc2 from the hepatopancreas of white shrimp showing symptoms of acute hepatopancreatic necrosis disease (AHPND) and evaluated the efficacy of this phage in preventing the mortality associated with V.

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Five lytic bacteriophages specific for Salmonella enterica and Escherichia coli were isolated from wastewater in Minnesota. These phages, designated vB_Sal_EH1, vB_Sal_EH2, vB_Sal_EH3, vB_Sal_EH4, and vB_Sal_EH7, were characterized, and their genomes were sequenced. Phylogenetic analysis showed that they grouped within the genus Epseptimavirus, with genome sizes ranging from 108,554 to 115,218 bp.

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Article Synopsis
  • The study tested the protective effects of a phage cocktail on Pacific white shrimp postlarvae, which were chosen for their ability to target various pathogenic Vibrio species.
  • Both culture-dependent and independent methods showed a significant reduction in Vibrio species levels after treatment with the phage cocktail.
  • Treated shrimp displayed less tissue damage and increased lipid accumulation, suggesting that phage therapy is an effective and environmentally safe alternative to antibiotics in shrimp farming.
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