X-linked juvenile retinoschisis associated with an RS1 in-frame deletion and bilateral central serous chorioretinopathy.

Purpose: To report the case of a patient with X-linked juvenile retinoschisis (XLRS), caused by an in-frame deletion of the RS1 gene, who presented visual loss due to bilateral central serous chorioretinopathy (CSC).Methods: Observational case report.

Results: A 34-year-old man, with type-A personality, presented with a one-month history of decreased visual acuity and metamorphopsia in his right eye.

AUTOSOMAL DOMINANT MÜLLER CELL SHEEN DYSTROPHY: Clinical, Histopathologic, and Genetic Assessment in an Extended Family With Long Follow-Up.

Background: Autosomal dominant Müller cell dystrophy is a rare condition we described in 1991. It is characterized by a striking sheen appearance on the retinal surface with progressive retinal changes leading to disorganization and atrophy with a decreased b-wave electroretinograms.

Materials And Methods: We examined 45 members of a 4-generation family.

Multimodal imaging in choroidal osteoma.

Purpose: To describe characteristics of choroidal osteomas (CO), using ocular ultrasound, fluorescein angiography, ultra-widefield retinal imaging, ultra-widefield autofluorescence, optical coherence tomography, enhanced-depth-imaging OCT, and OCT angiography (OCT-A).

Methods: Retrospective, observational case series study. Clinical records from patients with diagnosis of CO who underwent complete imaging evaluation were analyzed.

Safety of intravitreal quinupristin/dalfopristin in an animal model.

Aim: To determine whether different intravitreal doses of quinupristin/dalfopristin lead to electroretinographic or histological changes in the rabbit retina over one month period after injection.

Methods: Eighteen New Zealand white rabbits were divided into three treatment groups (groups 1 to 3) and different intravitreal doses of quinupristin/dalfopristin were tested in each group. The right eye was injected with the drug and the left eye received intravitreal injection of 5% dextrose water and served as control eye.

Paracentral cone dystrophy with tapetal-like sheen and mizuo phenomenon examined with different imaging techniques.

Purpose: To present a case report of a patient diagnosed with cone dystrophy, with an uncommon presentation of paracentral involvement, tapetallike sheen, and Mizuo phenomenon.

Methods: The patient underwent complete ophthalmic examination, repeated electroretinograms, fluorescein angiography, spectral-domain optical coherence tomography, autofluorescence, and different techniques for fundus photographs (color, infrared, red free).

Patient: Twenty-year-old male patient who manifested slight photofobia but was otherwise asymptomatic.

Multifocal electrophysiologic findings after intravitreal bevacizumab (avastin) treatment.

Purpose: To determine the short-term safety of intravitreal bevacizumab by multifocal electroretinography testing.

Methods: Thirty-one eyes with choroidal neovascularization, proliferative diabetic retinopathy, and retinal vein occlusion received intravitreal bevacizumab (2.5 mg/0.

Tractional retinal detachment after intravitreal injection of bevacizumab in proliferative diabetic retinopathy.

Purpose: To assess the short-term complications of a single dose of intravitreal bevacizumab in patients with proliferative diabetic retinopathy (PDR).

Methods: Retrospective review of 343 patients with PDR who were treated with intravitreal injection of bevacizumab (2.5 mg/0.

Vitrectomy with complete posterior hyaloid removal for ischemic central retinal vein occlusion: series of cases.

Background: Central retinal vein occlusion (CRVO) is a common retinal vascular disorder with potentially complications: (1) persistent macular edema and (2) neovascular glaucoma. No safe treatment exists that promotes the return of lost vision. Eyes with CRVO may be predisposed to vitreous degeneration.