Oxidative stress biomarkers in Senegal sole, Solea senegalensis, to assess the impact of heavy metal pollution in a Huelva estuary (SW Spain): seasonal and spatial variation.

The response of wild fish to heavy metals was studied in sole (Solea senegalensis) collected in 2004, 2005 and 2006 at three sampling sites from Huelva estuary (SW Spain), in the vicinity of a petrochemical and mining industry. Heavy metals As, Cd, Cu, Fe, Pb and Zn were analyzed in samples collected from sediment, water and tissue (liver) to examine their bioconcentration and effects in fish such as lipid peroxidation (LPO), catalase (CAT; EC 1.11.

Cyproterone acetate could counteract the benefits of estradiol valerate in oophorectomized cholesterol-fed rabbits.

Objective: The administration of hormonal replacement treatment to women with an intact uterus needs to be supplemented with progestogenic compounds to avoid endometrial hyperplasia. However, progestins may cancel the beneficial effects of estrogens on the cardiovascular system. The goal of this study was to examine the effects of adding cyproterone acetate to estradiol (E(2))on aorta atherogenesis.