Microbiological etiology and current resistance patterns in acute calculous cholecystitis.

Introduction: The current treatment for acute calculous cholecystitis (ACC) is early laparoscopic cholecystectomy, in association with appropriate empiric antibiotic therapy. In our country, the evolution of the prevalence of the germs involved and their resistance patterns have been scarcely described. The aim of the study was to analyze the bacterial etiology and the antibiotic resistance patterns in ACC.

Impact of empiric antibiotic therapy on the clinical outcome of acute calculous cholecystitis.

Purpose: Although mortality and morbidity of severe acute calculous cholecystitis (ACC) are still a matter of concern, the impact of inadequate empirical antibiotic therapy has been poorly studied as a risk factor. The objective was to assess the impact of the adequacy of empirical antibiotic therapy on complication and mortality rates in ACC.

Methods: This observational retrospective cohort chart-based single-center study was conducted between 2012 and 2016.

Scientific evidence of the duration of antibiotic treatment in intra-abdominal infections with surgical focus control.

A non-systematic review of the published scientific evidence has been carried out on the duration of empirical antibiotic treatment in surgical intra-abdominal infections (IIA) with effective focus control. Given the progressive increase in antibiotic resistance, it is urgent to have strategies to reduce the pressure on the microbiota. The American guidelines made by Mazuski et al.

Inflammatory Biomarkers and Clinical Judgment in the Emergency Diagnosis of Urgent Abdominal Pain.

Background: The early diagnosis of urgent abdominal pain (UAP) is challenging. Most causes of UAP are associated with extensive inflammation. Therefore, we hypothesized that quantifying inflammation using interleukin-6 and/or procalcitonin would provide incremental value in the emergency diagnosis of UAP.

Impact of thyroid nodular disease on 99mTc-sestamibi scintigraphy in patients with primary hyperparathyroidism.

Background: Primary hyperparathyroidism with coexisting thyroid nodular disease (TND) has been considered a contraindication for selective parathyroidectomy because the low sensitivity of preoperative localization studies, especially 99(m)Tc-sestamibi scanning (MIBI) and ultrasound. The aim of this study was to assess the impact of concomitant TND in the preoperative image studies.

Methods: A total of 236 consecutive patients who had parathyroidectomy for sporadic hyperparathyroidism and the preoperative localization study that was done with MIBI were reviewed.