Publications by authors named "Juan Jose Lopez Gomez"

Background And Aims: Parenteral nutrition (PN) composition could play a role in the management of systemic inflammatory response and intestinal barrier disruption. We aimed to evaluate changes in biomarkers of inflammation, oxidative status and intestinal permeability in patients with type 2 diabetes mellitus (T2DM) who received different PN lipid formulas.

Methods: This was a prospective study, including 94 patients with T2DM who received omega (n)-3 polyunsaturated fatty acids (PUFA)-enriched PN, a mixture of medium and long chain triglycerides (MCT/LCT) PN, or an olive oil-based PN.

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Article Synopsis
  • User-friendly assessment tools for malnutrition are essential, and this study focused on a personalized nutrition intervention using a new oral nutritional supplement and AI technology to track outcomes in malnourished patients.
  • The study included 65 patients and showed significant improvements over three months, with weight loss decreasing, and a drop in the prevalence of malnutrition and severe malnutrition.
  • Additionally, older patients experienced gains in muscle thickness, strength, and function, indicating that tailored interventions can effectively enhance nutrition and combat malnutrition in patients with disease-related issues.
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  • The weight-adjusted waist index (WWI) was evaluated for its ability to predict metabolic syndrome (MS) specifically among Caucasian individuals with obesity.
  • A study involving 2,162 obese Caucasian patients found that those in the highest WWI category were significantly more likely to have MS, with adjusted odds ratios demonstrating a clear trend linked to higher WWI levels.
  • Results indicated that the WWI has good predictive accuracy for MS with a cut-off value of 11.59, showing a sensitivity of 70% and specificity of 93.4%.
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Objectives: The aim of this investigation was to evaluate the discrepancies between bioelectrical impedance analysis (BIA) and computed tomography (CT) in assessing skeletal muscle mass and identifying low muscle mass in patients with colorectal cancer.

Methods: This study recruited 137 patients with colorectal cancer from February 2028 to December 2023. CT scans were analyzed at the Lumbar 3 vertebral level to determine the area of skeletal muscle, which was then utilized to estimate whole-body skeletal muscle mass.

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(1) Background: The aim was to validate an AI-based system compared to the classic method of reading ultrasound images of the rectus femur (RF) muscle in a real cohort of patients with disease-related malnutrition. (2) Methods: One hundred adult patients with DRM aged 18 to 85 years were enrolled. The risk of DRM was assessed by the Global Leadership Initiative on Malnutrition (GLIM).

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Introduction: The effects of the rs822393 variant of ADIPOQ gene on metabolic parameters such as insulin resistance and adiponectin levels following weight loss through dietary intervention are still uncertain. The aim of this study was to evaluate the role of rs822393 of ADIPOQ gene on adiponectin levels and metabolic parameters after weight loss with a high-fat hypocaloric diet with Mediterranean pattern during 12 weeks.

Methods: A population of 283 patients with obesity was allocated to a dietary intervention trial with a high-fat hypocaloric diet during 12 weeks.

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Background: amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a progressive course. The current prevalence is between 3 and 6 cases/100,000. Malnutrition is closely related to patient prognosis in ALS.

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Background & Aims: Some studies have reported links between 25-hydroxyvitamin D levels and the presence of obesity and some genetic variants. The aim of our design was to evaluate the effects of rs2282679 genetic variant of CG gene on 25-hydroxyvitamin D levels, weight loss and metabolic parameters after a robotic sleeve gastrectomy in premenopausal females with obesity.

Methods: 76 participants were enrolled.

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Background: Adiponectin is one of the most important adipokines in human beings. Obesity and sarcopenia are associated with a low-level chronic inflammatory status, and adiponectin plays an anti-inflammatory role.

Aims: The objective of the current work was to study the association between muscle mass, determined via bioelectrical impedance (BIA), and circulating adiponectin levels among obese patients with metabolic syndrome who are older than 60 years of age.

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Objectives: To propose the grounds for "diabetic sarcopenia" as a new comorbidity of diabetes, and to establish a muscle screening algorithm proposal to facilitate its diagnosis and staging in clinical practice.

Method: A qualitative expert opinion study was carried out using the nominal technique. A literature search was performed with the terms "screening" or "diagnostic criteria" and "muscle loss" or "sarcopenia" and "diabetes" that was sent to a multidisciplinary group of 7 experts who, in a face-to-face meeting, discussed various aspects of the screening algorithm.

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Objectives: Sarcopenia is characterized by the loss of muscle mass. Skeletal muscle can produce and secrete different molecules called myokines. Irisin and myostatin are antagonistic myokines, and to our knowledge, no studies of both myokines have been conducted in patients with disease-related malnutrition (DRM).

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Introduction: The potential influence of a Mediterranean diet (MD) on PhA values has been little researched. The aim of this study was to investigate the association between adherence of a MD and PhA on adult sample population with obesity and metabolic syndrome.

Methods: We conducted a cross-sectional study in 331 patients with obesity and metabolic syndrome.

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Article Synopsis
  • This Special Issue focuses on the diagnosis of disease-related malnutrition (DRM) in clinical settings.
  • It emphasizes morphofunctional nutritional assessments, which involve evaluating physical and functional aspects of nutrition.
  • The goal is to improve understanding and management of malnutrition in patients, aiding healthcare professionals in providing better care.
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Unlabelled: Nutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between the parameters of body mass and quality of ultrasonography with other parameters of morphofunctional assessment in patients with disease-related malnutrition (DRM).

Methods: A cross-sectional study was developed on 144 patients diagnosed with DRM according to the Global Leadership Initiative on Malnutrition (GLIM) criteria.

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Introduction: Under physical exercise conditions, muscles can synthetise and release myokines and these molecules can exert paracrine and endocrine actions. Females with obesity have a sedentary lifestyle with alterations in myokine levels.

Objective: The aim of our study was to evaluate the effect of physical exercise on myokine levels, anthropometric parameters, clinical data, impedance parameters, and muscle ultrasound data in sedentary females with obesity.

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Objectives: The beta-2 adrenergic receptor (ADRB2) is involved in energy balance regulation. The objective of our study was to evaluate the role of the rs1042714 genetic variant of ADRB2 gene on weight loss, body composition, and metabolic changes secondary to partial meal replacement (pMR) hypocaloric diet in women with obesity.

Methods: We conducted an interventional study in 95 premenopausal women with body mass index ≥ 35 kg/m.

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Introduction: Serum resistin levels have been associated with obesity, visceral fat, and insulin resistance. Its relationship with muscle mass has been less evaluated.

Objectives: to evaluate the relationship between muscle mass determined by electrical bioimpedance and circulating resistin levels in obese women over 60 years of age.

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  • Hip fractures in patients aged 75 and older are highly disabling and often associated with malnutrition and sarcopenia, which is the loss of muscle mass and strength.
  • A study evaluated 186 patients hospitalized for hip fractures, revealing that 37.1% were at nutritional risk, 16.7% were malnourished, and a significant percentage of the patients had sarcopenia.
  • Results showed that patients with sarcopenia exhibited lower body mass index, older age, worse functional status, and greater disease burden, highlighting the interconnectedness of these conditions in older adults.
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Objectives: an expert report is presented on the situation of loss of muscle mass in people with type 2 diabetes mellitus (T2DM), with a proposal of what the clinical approach to this comorbidity should be, based on the evidence from the literature and clinical experience. Method: a qualitative expert opinion study was carried out using the nominal approach. A literature search on diabetes and muscle was made and submitted to a multidisciplinary group of 7 experts who through a face-to-face meeting discussed different aspects of the role of muscle mass in T2DM.

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Introduction: To evaluate the adequacy of TSH suppression therapy (TSHst) at the first disease assessment and the last follow-up visit.

Methods: Retrospective observational study of those patients under follow-up of DTC in a reference hospital.

Results: 216 patients (79.

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Objective: To evaluate metabolic control and satisfaction with a telemedicine diabetes education programme for the initiation of flash glucose monitoring (FGM) in type 1 diabetes.

Material And Methods: Prospective study in 48 patients (52.1% women, 22.

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Introduction: hyponatremia is the most frequent disturbance in hospitalized patients. This situation may influence the therapeutic approach in patients with total enteral tube feeding (TEN). Objective: to study the prevalence of hyponatremia and the clinical factors that are associated with increased risk in a population with TEN.

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Introduction: Flash glucose monitoring (FGM) improves some glycaemic control variables and quality of life parameters.

Objective: Our aim was to evaluate the quality of life and glycaemic control parameters after initiating FGM in patients with type 1 diabetes (DM1) in clinical practice.

Material And Methods: A prospective observational study in DM1 patients that started using FGM between June 2019 and April 2020.

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Background: The Enhanced Recovery After Surgery (ERAS) care pathways include evidence-based items designed to accelerate recovery after surgery. Interdisciplinarity is one of the key points of ERAS programs.

Objective: To prepare a consensus document among the members of the Nutrition Area of the Spanish Society of Endocrinology and Nutrition (SEEN) and the Spanish Group for Multimodal Rehabilitation (GERM), in which the goal is to homogenize the nutritional and metabolic management of patients included in an ERAS program.

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