Publications by authors named "Juan J Puigbo"
Article Synopsis
- The study investigated capillary damage in skeletal muscles of patients with advanced Chagas' disease compared to healthy subjects, focusing on the vastus lateralis muscle.
- Findings revealed a reduced capillary-to-fibre ratio and decreased capillary proximity to specific muscle fibre types in patients, indicating significant structural changes at the cellular level.
- The observed capillary abnormalities suggest a potential autoimmune component in chronic Chagas' disease, which could contribute to impaired muscle function in affected individuals.
Study Objective: This study was designed to evaluate the peripheral muscle metabolic and structural characteristics in patients with advanced Chagas disease (ChD), and whether they were related with exercise performance.
Design: Cross-sectional study.
Setting: Outpatient cardiomyopathy clinic of a university hospital.
BACKGROUND: In a prospective epidemiological study of chronic Chagas' disease, several clinical and echocardiographic variables were analyzed as predictors of mortality. METHODS: Among 960 subjects seropositive for Chagas' disease who were examined between June 1981 and June 1992, 283 had echocardiograms. RESULTS: During a mean follow-up period of 48.
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