Upscaling Mixing-Controlled Reactions in Unsaturated Porous Media.

We study mixing-controlled chemical reactions in unsaturated porous media from a pore-scale perspective. The spatial heterogeneity induced by the presence of two immiscible phases, here water and air, in the pore space generates complex flow patterns that dominate reactive mixing across scales. To assess the impact of different macroscopic saturation states (the fraction of pore volume occupied by water) on mixing-controlled chemical reactions, we consider a fast irreversible reaction between two initially segregated dissolved species that mix as one solution displaces the other in the heterogeneous flow field of the water phase.

Comparison of IOTA three-step strategy and logistic regression model LR2 for discriminating between benign and malignant adnexal masses.

Aims: To compare the diagnostic performance of two ultrasound-based diagnostic systems for the classification of benign or malignant adnexal masses, the three-step strategy and the predictive logistic regression model LR2, both proposed by the International Ovarian Tumour Analysis (IOTA) Group.

Material And Methods: Prospective observational study at a single centre that included patients diagnosed with a persistent adnexal mass by transvaginal ultrasound over a period of two years. They were evaluated by a non-expert sonographer by applying the three-step diagnostic strategy and the LR2 predictive model to classify the masses as benign or malignant.

Postoperative Intestinal Fistula in Primary Advanced Ovarian Cancer Surgery.

Background: Advanced ovarian cancer (AOC) requires an aggressive surgery with large visceral resections in order to achieve an optimal or complete cytoreduction and increase the patient's survival. However, the surgical aggressiveness in the treatment of AOC is not exempt from major complications, such as the gastrointestinal fistula (GIF), which stands out among others due to its high morbidity and mortality.

Methods: We evaluated the clinicopathological features in patients with AOC and their association with GI.

Prospective case controlled clinical study of post-endodontic pain after rotary root canal preparation performed by a single operator.

Objectives: The aim of this study was to assess the influence of the shaping technique on incidence, intensity, duration and type of postoperative pain (PP).

Methods: Root canal treatments were carried out with rotary instrumentation (n=80) during a single-visit, and data about pre-treatment conditions were collected. Patients were given a questionnaire to record the presence or absence of post-endodontic pain, its duration and level of discomfort.

Scaling of convective mixing in porous media.

Convective mixing in porous media is triggered by a Rayleigh-Bénard-type hydrodynamic instability as a result of an unstable density stratification of fluids. While convective mixing has been studied extensively, the fundamental behavior of the dissolution flux and its dependence on the system parameters are not yet well understood. Here, we show that the dissolution flux and the rate of fluid mixing are determined by the mean scalar dissipation rate.

Overcoming challenges of ovarian cancer stem cells: novel therapeutic approaches.

Understanding the genetic and molecular mechanisms of ovarian cancer has been the focus of research efforts working toward the greater goal of improving cancer therapy for patients with residual disease after initial treatment with conventional surgery and neoadjuvant chemotherapy. The focus of this review will be centered on new therapeutic strategies based on Cancer Stem Cells studies of chemoresistant subpopulations, the prevention of metastasis, and individualized therapy in order to find the most successful combination of treatments to effectively treat human ovarian cancer. We reviewed recent literature (1993-2011) of novel treatment approaches to ovarian cancer stem cells.

Relationship between postendodontic pain, tooth diagnostic factors, and apical patency.

This study compares the incidence, degree, and length of postoperative pain in 300 endodontically treated teeth, with and without apical patency, in relation to some diagnostic factors (vitality, presence of preoperative pain, group, and mandible of treated tooth). Of the questionnaires received back, apical patency was maintained during shaping procedures with a #10 K-file in one group (n = 115) and not in the other (n = 121). There was significantly less postendodontic pain when apical patency was maintained in nonvital teeth.

Appraisal of psychomotor skills of dental students at University Complutense of Madrid.

The aim of this study was to evaluate the psychomotor skills of the dental students at University Complutense of Madrid (UCM), using a battery of psychometric tests. The sample comprised 306 students of the 1st, 2nd, 3rd and 4th years of Odontology, who, during the last month of the academic term, took the test on rotation of solid shapes, the Embedded Figures test in its group form (GEFT), the O'Connor Tweezer test, the MacQuarrie test for mechanical ability and the indirect vision test. Before these tests began, some personal data of all students were collected.

Ductal carcinoma in situ of the breast: a comparative analysis of histology, nuclear area, ploidy, and neovascularization provides differentiation between low- and high-grade tumors.

Ductal carcinoma in situ (DCIS) is a heterogeneous group of lesions that has been subdivided into three types: well differentiated (grade I), moderately differentiated (grade II), and poorly differentiated (grade III). Forty-five cases of DCIS were analyzed for image analysis: nuclear area, DNA ploidy, and vascularization in order to establish a more precise correlation between the histologic grade and these morphometric parameters. Our results confirm that the mean nuclear area, DNA ploidy, and microvessel density (MVD) progressively increased from DCIS grade I to DCIS grade III.