Background And Aim: There is a lack of instruments that focus on the specific health-related quality of life (HRQOL) issues that affect older people with cancer. The aim of this study was to develop a HRQOL questionnaire module to supplement the European Organisation for Research and Treatment of Cancer (EORTC) core questionnaire, the EORTC QLQ-C30 for older (>70years) patients with cancer.
Methods: Phases 1-3 were conducted in seven countries following modified EORTC Quality of Life Group guidelines for module development.
Aim: The aim of this paper is to systematically review the use and validation of HRQOL instruments in older cancer patients.
Method: A systematic review of 5 databases and 3 research registers identified studies reporting the use and validation of HRQOL instruments in cancer patients aged over 65 years from 1995 to mid 2007.
Results: Thirty-one studies reported the use of HRQOL measures in older people, using a range of generic and disease-specific instruments.