Publications by authors named "Juan F Oteo-Dominguez"
Article Synopsis
- The article reviews the 2023 activity report from the Interventional Cardiology Association of the Spanish Society of Cardiology, highlighting key trends in interventional cardiology practices in Spain.
- A survey involving 119 hospitals revealed a slight decrease in diagnostic studies but an increase in percutaneous coronary interventions (PCI), with a notable rise in the use of drug-coated balloons and techniques for plaque modification.
- The findings indicate a stabilization in coronary interventions while showcasing a growth in complex procedures, particularly for valvular and nonvalvular structural heart diseases, with primary PCI becoming the leading treatment for myocardial infarction.
Objectives: Extended septal myectomy and alcohol septal ablation are 2 invasive treatments for hypertrophic obstructive cardiomyopathy. Our goal was to compare which of these techniques achieved a higher reduction in gradients, improvement in New York Heart Association (NYHA) functional class and reduction in medical treatment.
Methods: It is a single-centre observational and retrospective analysis.
Article Synopsis
- This article reports on the annual activities of the Interventional Cardiology Association of the Spanish Society of Cardiology for 2022.
- A total of 111 centers participated, revealing a 4.8% increase in diagnostic studies and a significant 22% rise in PCIs on the left main coronary artery, while the overall PCI numbers remained stable.
- Key trends included a preference for the radial approach in 94.9% of cases, increased use of drug-eluting balloons and intracoronary imaging, and a continuous rise in noncoronary procedures, especially those related to heart valve and structural heart issues.
A 21-year-old woman with a history of atopy, peripheral eosinophilia, Wolf-Parkinson-White syndrome, and 5 episodes of myocarditis was diagnosed with eosinophilic myocarditis. Despite adequate immunosuppressive treatment and resolution of the myocarditis episode, the patient developed dilated cardiomyopathy and presented with worsening of her functional class. Finally, genetic testing unveiled an additional diagnosis: Danon disease.
View Article and Find Full Text PDFBackground: The potential benefit of using larger or smaller transcatheter heart valves (THV) in patients with borderline aortic annulus measurement (BAM) remains uncertain. The objective of this study was to evaluate the clinical outcomes associated with the selection of larger or smaller THV in the context of BAM.
Methods: This was a multicenter observational study including patients who underwent transcatheter aortic valve replacement with the SAPIEN 3 or SAPIEN 3 Ultra-valve systems (Edwards Lifesciences, Irvine, CA) from April 2014 to June 2021.
Risk of Infective Endocarditis Associated with Transcatheter Aortic Valve Implantation versus Surgical Aortic Valve Replacement: A Propensity Score-Based Analysis.
J Clin Med
January 2023
Article Synopsis
- Infective endocarditis (IE) is a serious complication following surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI), and this study aimed to compare the risk of IE between the two procedures.
- The study included 355 SAVR and 278 TAVI patients, finding that TAVI had a higher occurrence of early IE (3.2% vs. 0.3%) while overall IE risk was similar in both procedures when analyzed using propensity scores.
- Factors linked to a higher risk of IE in TAVI patients included younger age, complicated diabetes, chronic obstructive pulmonary disease (COPD), advanced heart failure, and peripheral arteriopathy.
Objective: In patients with advanced heart failure, the intravascular optical coherence tomography (OCT) of subsegmental pulmonary artery measurements is correlated with right heart catheterization parameters. Our aim was to study the prognostic value of pulmonary OCT, right heart catheterization data, and the echocardiographic estimation of pulmonary pressure in patients studied for elective heart transplants.
Methods: This research is an observational, prospective, multicenter study involving 90 adults with a one-year follow-up.
Article Synopsis
- There is limited understanding of how gender affects the clinical presentation, treatment, and outcomes of patients experiencing cardiogenic shock (CS), particularly in a hospital setting.
- The study aimed to explore gender-related differences in characteristics, management, and in-hospital mortality among CS patients, while also evaluating the prognostic accuracy of the SCAI classification for predicting mortality by sex.
- An analysis of 163 CS patients showed that women were less likely to smoke and had lower rates of certain conditions compared to men, but in-hospital survival rates were similar across genders, indicating no significant differences in outcomes.
Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents: EPIC05-Sierra75 study.
J Geriatr Cardiol
May 2022
Article Synopsis
- The study aimed to evaluate the outcomes of elderly patients (over 75 years) undergoing percutaneous transluminal coronary intervention (PCI) using an antithrombotic strategy that considers their individual risks for bleeding and ischemic events.
- The research included 1,064 patients and found that the incidence of major adverse cardiovascular events and bleeding was lower in this tailored treatment group compared to a control group, with no cases of stent thrombosis in those receiving shorter dual antiplatelet therapy.
- The conclusion indicates that a risk-adjusted antithrombotic protocol for elderly patients after revascularization with the latest stent technology may lead to better health outcomes regarding both bleeding and ischemic events.
Introduction And Objectives: Endomyocardial biopsy (EMB) is the only technique able to establish an etiological diagnosis of myocarditis or inflammatory cardiomyopathy (ICM). The aim of this study was to analyze the clinical profile, outcomes, and prognostic factors of patients with suspected myocarditis/ICM undergoing EMB.
Methods: We retrospectively analyzed the clinical characteristics, histological findings, and follow-up data of all patients with suspected myocarditis or ICM who underwent EMB between 1997 and 2019 in a Spanish tertiary hospital.
Background: Cardiac allograft vasculopathy (CAV) remains a major cause of morbidity and mortality among long-term heart transplant recipients. There is an unmet need for a non-invasive biomarker of CAV that could obviate the need to perform surveillance coronary angiograms in these patients. Our aim was to evaluate the performance of Donor-derived Cell Free DNA (dd-cfDNA) as a biomarker of CAV.
View Article and Find Full Text PDFImmune checkpoint inhibitors (ICIs) have revolutionized cancer therapy over the last decade. Pembrolizumab, a humanized monoclonal IgG4 antibody, binds to the programmed death 1 (PD-1) receptor, blocking its interaction with programmed death-ligand 1 (PD-L1) and thereby increasing the anti-tumor activity of the host immune system. These drugs are associated with immune-mediated side effects that can be life threatening, and myocarditis is among the most serious events.
View Article and Find Full Text PDFBackground: Transcatheter mitral valve repair (TMVR) could improve survival in functional mitral regurgitation (FMR), but it is necessary to consider the influence of left ventricular ejection fraction (LVEF). Therefore, we compare the outcomes after TMVR with Mitraclip between two groups according to LVEF.
Methods: In an observational registry study, we compared the outcomes in patients with FMR who underwent TMVR with and without LVEF <30%.
Article Synopsis
- The study focuses on improving outcomes for patients with cardiogenic shock (CS), particularly those requiring mechanical circulatory support (MCS), by analyzing a care program implemented by a multidisciplinary team in a regional hospital network from 2014 to 2019.
- A total of 130 patients were examined, with a majority being middle-aged men; most cases were due to heart failure or myocardial infarction, and 81% of patients used MCS, primarily extracorporeal membrane oxygenation (ECMO).
- The program achieved a 57% survival rate to discharge, suggesting that a coordinated approach with specialized teams significantly benefits patients in critical conditions like refractory CS.
Large dissecting intramural haematoma of the oesophagus and stomach and major gastro-oesophageal bleeding after transoesophageal echocardiography during transcatheter aortic valve replacement procedures.
Eur Heart J Cardiovasc Imaging
August 2018
TIOMAX: A Spanish Multicenter Registry of the real-world use of the TItanium OptiMAX biostent: TIOMAX: Registro Español Multicéntrico Del Biostent De Titanio OptiMAX En La Vida Real.
Catheter Cardiovasc Interv
August 2018
Objectives: To compare the safety and efficacy of the new cobalt-chromium bioactive stent Titan Optimax (Hexacath, France) with its predecessor, Titan-2 .
Background: The TIOMAX registry includes 784 patients who underwent percutaneous coronary intervention with these stents in 21 Spanish hospitals.
Methods: Analysis of all patients in the registry without exclusion criteria, candidates for revascularization (March-2013/July-2014).
Introduction And Objectives: The beneficial effect of coronary collateral circulation (CC) in patients with ST-segment elevation myocardial infarction is controversial. The aim of this study was to evaluate the impact of CC before reperfusion with primary angioplasty (PA) on the long-term prognosis of these patients.
Methods: Retrospective observational study of a cohort of 947 patients treated with PA and TIMI grade ≤ 1 flow in a single center from 2005 to 2013.
Dual Antiplatelet Therapy for 6 Months vs 12 Months After New-generation Drug-eluting Stent Implantation: Matched Analysis of ESTROFA-DAPT and ESTROFA-2.
Rev Esp Cardiol (Engl Ed)
October 2015
Introduction And Objectives: The recommendation for dual antiplatelet therapy following drug-eluting stent implantation ranges from 6 months to 12 months or beyond. Recent trials have suggested the safety of a 6-month dual antiplatelet therapy regimen, yet certain caveats to these studies limit the applicability of this shorter duration dual antiplatelet therapy strategy in real world settings.
Methods: A registry was constructed with consecutive recruitment of patients undergoing new-generation drug-eluting stent implantation and prescribed 6 months of dual antiplatelet therapy.
Background: The optimal duration of dual antiplatelet therapy (DAPT) following second-generation drug-eluting stent (DES) implantation is still debated.
Objectives: The aim of this study was to test the noninferiority of 6 versus 12 months of DAPT in patients undergoing percutaneous coronary intervention with second-generation DES.
Methods: The SECURITY (Second Generation Drug-Eluting Stent Implantation Followed by Six- Versus Twelve-Month Dual Antiplatelet Therapy) trial was a 1:1 randomized, multicenter, international, investigator-driven, noninferiority study conducted from July 2009 to June 2014.
The safety and effectiveness of angioplasty for chronic total occlusions of the coronary arteries have been demonstrated in several studies, but the success rate is less than for conventional interventions. The complexity of the procedures presents a major challenge. In selected cases, performing angioplasty of the occlusion via a retrograde approach has been used as an alternative.
View Article and Find Full Text PDFPrimary cardiac sarcomas are rapidly progressive malignant tumors. No good therapeutic option is known. In recent years, heart transplantation has sometimes been performed in selected patients with cardiac sarcoma.
View Article and Find Full Text PDFWe report the case of a 33-years-old woman, smoker and taking oral contraceptives, who presented to the emergency room with an anterior ST-elevation myocardial infarction. Thrombolytic treatment was initiated and a few minutes after, chest pain returned and an inferior ST-segment-elevation infarction was diagnosed at that moment. Catheterization revealed multiple embolic occlusion of coronary branches.
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