Publications by authors named "Juan Eduardo Flores-Bautista"
Association Analysis Between the Functional Single Nucleotide Variants in miR-146a, miR-196a-2, miR-499a, and miR-612 With Acute Lymphoblastic Leukemia.
Silvia Jiménez-Morales Juan Carlos Núñez-Enríquez Jazmín Cruz-Islas Vilma Carolina Bekker-Méndez Elva Jiménez-Hernández Juan Eduardo Flores-Bautista
Front Oncol
November 2021
Article Synopsis
- Acute lymphoblastic leukemia (ALL) is linked to both genetic and environmental factors, with single nucleotide polymorphisms (SNPs) in specific genes potentially increasing risk in pediatric populations in Mexico.
- A multicenter study was conducted comparing children diagnosed with ALL to healthy controls, examining the impact of SNPs rs2910164, rs12803915, rs11614913, and rs3746444 through DNA analysis.
- The results indicated a significant association of the rs3746444 SNP with a higher risk of developing ALL, particularly in males, highlighting the need for further research on the genetic mechanisms behind ALL.
Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A Report From the Mexican Interinstitutional Group for the Identification of the Causes of Childhood Leukemia.
Aurora Medina-Sanson Juan Carlos Núñez-Enríquez Eduardo Hurtado-Cordova María Luisa Pérez-Saldivar Anayeli Martínez-García Juan Eduardo Flores-Bautista
Front Oncol
September 2020
Acute lymphoblastic leukemia (ALL) is the main type of cancer in children. In Mexico and other Hispanic populations, the incidence of this neoplasm is one of the highest reported worldwide. Functional polymorphisms of various enzymes involved in the metabolism of xenobiotics have been associated with an increased risk of developing ALL, and the risk is different by ethnicity.
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