Int J Mol Sci
July 2024
This article follows-up on our recently published work, which evaluated the impact of the addition of an alfalfa leaf-derived adsorbent in the aflatoxin B (AFB)-contaminated diet in regard to the production parameters, blood cell count, serum biochemistry, liver enzymes, and liver histology of turkey poults. This paper presents complementary results on microbial community, ileal morphology, barrier function, and immunity. For this purpose, 350 1-day-old female turkey poults were randomly distributed into five groups: (1) Control, AFB-free diet; (2) AF, AFB-contaminated diet at 250 ng/g; (3) alfalfa, AFB-free diet + 0.
View Article and Find Full Text PDFBirds, including canaries and other birds, have become increasingly popular as pets. Bird fairs, where breeders gather and show their production in a championship setting, present a setting for possible spp. contamination and transmission.
View Article and Find Full Text PDFA recent study published data on the growth performance, relative weights of the organs of the gastrointestinal tract, liver histology, serum biochemistry, and hematological parameters for turkey poults fed an experimental diet contaminated with aflatoxin B (AFB) and humic acids (HA) extracted from vermicompost. The negative effects of AFB (250 ng AFB/g of feed) were significantly reduced by HA supplementation (0.25% /), suggesting that HA might be utilized to ameliorate the negative impact of AFB from contaminated diets.
View Article and Find Full Text PDFInt J Mol Sci
November 2023
The selection of components within a formulation or for treatment must stop being arbitrary and must be focused on scientific evidence that supports the inclusion of each one. Therefore, the objective of the present study was to obtain a formulation based on ascorbic acid (AA) and Eudragit FS 30D microparticles containing curcumin-boric acid (CUR-BA) considering interaction studies between the active components carried out via Fourier transform infrared spectrometry (FTIR) and differential scanning calorimetry (DSC) to minimize antagonistic effects, and comprehensively and effectively treat turkey poults infected with (). The DSC and FTIR studies clearly demonstrated the interactions between AA, BA, and CUR.
View Article and Find Full Text PDFThis study aims to evaluate the efficacy of humic acid (HA) from worm compost as an adsorbent for aflatoxin B (AFB) in turkey poults. The experiment involved the inclusion of 0.25% (w/w) HA in the diet of turkey poults consuming aflatoxin-contaminated feed (250 ng AFB/g).
View Article and Find Full Text PDFEnterococcus cecorum (EC) has been associated with septicemia and early mortality in broiler chickens. There is limited research investigating the pathogenicity of EC field strains obtained from affected birds. The purpose of this study was to evaluate the effect of in-ovo administration into the amnion with different EC field isolates at d 18 of embryogenesis (DOE18).
View Article and Find Full Text PDFA mixed spp. challenge model was designed to assess the effects of challenge on broiler chicken performance, intestinal integrity, and the gut microbiome for future use to evaluate alternative strategies for controlling coccidiosis in broiler chickens. The experimental design involved broiler chickens divided into two groups: a control group (uninfected) and a positive control group, infected with (EA), (EM), and (ET).
View Article and Find Full Text PDFIntroduction: Coccidiosis caused by the spp., an Apicomplexan protozoon, is a major intestinal disease that affects the poultry industry. Although most cases of coccidiosis are subclinical, infections impair bird health and decrease overall performance, which can result in compromised welfare and major economic losses.
View Article and Find Full Text PDFEssential oils (EO) affect performance, intestinal integrity, bone mineralization, and meat quality in broiler chickens subjected to cyclic heat stress (HS). Day-of-hatch Cobb 500 male broiler chicks ( = 475) were randomly divided into four groups. Group 1: No heat stress (Thermoneutral) + control diets with no antibiotics; Group 2: heat stress control + control diets; Group 3: heat stress + control diets supplemented with thymol chemotype (45 ppm) and herbal betaine (150 ppm) formulation EO1; Group 4: heat stress + control diets supplemented with phellandrene (45 ppm) and herbal betaine (150 ppm) formulation EO2.
View Article and Find Full Text PDFIntroduction: Drug-sensitive live coccidiosis vaccines have been used to control coccidiosis and renew drug sensitivity in commercial chicken operations. However, only limited species coverage vaccines have been available for commercial turkey producers. This study aimed to assess the effect of an vaccine candidate, with and without amprolium intervention, on performance and oocyst shedding.
View Article and Find Full Text PDFChronic stress is recognized as a secret killer in poultry. It is associated with systemic inflammation due to cytokine release, dysbiosis, and the so-called leaky gut syndrome, which mainly results from oxidative stress reactions that damage the barrier function of the cells lining the gut wall. Poultry, especially the genetically selected broiler breeds, frequently suffer from these chronic stress symptoms when exposed to multiple stressors in their growing environments.
View Article and Find Full Text PDFOutbreaks of histomonosis in turkeys are typically initiated by the ingestion of contaminated embryonated eggs of , potentially present in earthworms and mechanical vectors. Once an outbreak is started, infected turkeys can transmit the disease by horizontal transmission. Factors influencing horizontal transmission of histomonosis are poorly understood.
View Article and Find Full Text PDFThe goal of this research was to assess cyclic heat stress on gut permeability, bone mineralization, and meat quality in chickens. Two separate trials were directed. 320 day-of-hatch Cobb 500 male chicks were randomly assigned to four thermoneutral (TN) and four cyclic heat stress (HS) chambers with two pens each, providing eight replicates per treatment in each trial (n = 20 chicks/replicate).
View Article and Find Full Text PDFFront Vet Sci
February 2022
The gut microbiota has been designated as a hidden metabolic 'organ' because of its enormous impact on host metabolism, physiology, nutrition, and immune function. The connection between the intestinal microbiota and their respective host animals is dynamic and, in general, mutually beneficial. This complicated interaction is seen as a determinant of health and disease; thus, intestinal dysbiosis is linked with several metabolic diseases.
View Article and Find Full Text PDFJ Anim Sci Biotechnol
February 2021
Background: Interest in the use of natural feed additives as an alternative to antimicrobials in the poultry industry has increased in recent years because of the risk of bacterial resistance. One of the most studied groups are polyphenolic compounds, given their advantages over other types of additives and their easy potentiation of effects when complexes are formed with metal ions. Therefore, the objective of the present study was to evaluate the impact of dietary supplementation of copper acetate (CA), curcumin (CR), and their combination (CA-CR) against Salmonella Typhimurium colonization, intestinal permeability, and cecal microbiota composition in broiler chickens through a laboratory Salmonella infection model.
View Article and Find Full Text PDFFront Vet Sci
August 2020
The effects of administration of a defined lactic acid microbiota (LAM), previously isolated from adult hens, in the cecae microbiota structure and colonization after exposure to virulent during the hatching phase of broiler chickens were evaluated. Embryos inoculated with LAM showed a significant ( < 0.05) reduction of colonization at day-of-hatch (DOH) and day (d) 7.
View Article and Find Full Text PDFAn experiment was conducted to quantify the timing and magnitude of the effects of coccidiosis vaccination on the growth performance, apparent ileal digestibility (AID) of nutrients and energy, intestinal morphology, and plasma carotenoids and nitric oxide in broilers. Treatment groups consisted of 3 coccidiosis control methods [unvaccinated, unmedicated (NC), in-feed chemical coccidiostat (PC), and live oocyst vaccination (VAC) at day of hatch] administered to male Cobb broilers reared in floor pens. Body weight gain (BWG), feed intake (FI), and feed conversion ratio (FCR) were determined at 12, 16, 20, 28, and 36 d.
View Article and Find Full Text PDFcauses severe gastrointestinal diseases, which include necrotic enteritis (NE) in chickens, a deadly disease worldwide. We report here the draft genome sequence of strain TAMU, which was used in developing an NE chicken challenge model. This TAMU genome sequence will aid in advancing potential intervention strategies to reduce NE pathogenesis.
View Article and Find Full Text PDFThe aim of the present study was to evaluate the effect of a commercial direct-fed microbial (DFM) on aflatoxin B1 toxic effects, performance, and biochemical and immunologic parameters in broiler chickens. Ninety 1-day-old Cobb 500 male broiler chicks were raised in floor pens for a period of 21 days. Chicks were neck-tagged, individually weighed, and randomly allocated to one of three groups: Negative control (basal feed), aflatoxin B1 (basal feed + 2 ppm AFB1), and DFM (basal feed + 2 ppm AFB1 + direct-fed microbial).
View Article and Find Full Text PDFTwo experimental models were conducted to evaluate and compare the effect of ascorbic acid (AA) or curcumin formulated in a solid dispersion (SD-CUR) as prophylactic or therapeutic alternatives to prevent or control Enteritidis (SE) infection in broiler chickens. In the prophylactic model, dietary administration of AA showed a significant reduction in SE counts in crop compared to the positive control (PC) group ( < 0.05), whereas in cecal tonsils (CT), SD-CUR significantly reduced SE recovery.
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