Radiation-Induced Bystander Effect: Loss of Radioprotective Capacity of Rosmarinic Acid In Vivo and In Vitro.

In radiation oncology, the modulation of the bystander effect is a target both for the destruction of tumor cells and to protect healthy cells. With this objective, we determine whether the radioprotective capacity of rosmarinic acid (RA) can affect the intensity of these effects. Genoprotective capacity was obtained by determining the micronuclei frequencies in in vivo and in vitro assays and the cell survival was determined by the (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay) (MTT) assay in three cell lines (PNT2, TRAMPC1 and B16F10), both in direct exposure to X-rays and after the production of radiation-induced bystander effect.

A New Therapeutic Application of Platelet-Rich Plasma to Chronic Breast Wounds: A Prospective Observational Study.

The aim of this study was to investigate the usefulness of platelet-rich plasma (PRP) treatment for chronic wounds (CWs) of the breast. A prospective study was performed in 23 patients with CW of the breast who were treated with PRP. The procedure was repeated until the wound was closed completely.

Influence of Acromial Morphologic Characteristics and Acromioclavicular Arthrosis on the Effect of Platelet-Rich Plasma on Partial Tears of the Supraspinatus Tendon.

The purposes of this study were to determine the medium-term effect of ultrasound-guided infiltration of platelet-rich plasma (PRP) on partial tears of the supraspinatus tendon (SST) and to identify prognostic indicators of an unfavorable outcome. Over a period of 4 years, patients with a partial SST tear smaller than 1.5 cm referred for ultrasound-guided PRP infiltration (1 mL) for shoulder pain lasting more than 3 months were recruited consecutively.

A New Treatment for Mammillary Fistulas Using Ultrasound-Guided Percutaneous Needle Electrolysis.

The aim of this study was to investigate the efficacy of ultrasound-guided percutaneous needle electrolysis (PNE) in mammillary fistulas (MFs). A prospective study was performed in 18 patients with MF who were treated with the PNE technique. The technique was repeated in the case of no response or recurrence.

Effect of different ergonomic supports on muscle activity of dentists during posterior composite restoration.

Background: The aim of this study was to evaluate the effect of different ergonomic supports on the muscle activity of two trunk muscles while a group of dentists performed a common dental procedure on a phantom head, divided into three tasks.

Methods: A one-way repeated measures study (ANOVA) was conducted on a group of 36 dentists. The middle trapezius and lumbar erector spinae muscles were measured with and without the use of different ergonomic supports (ergonomic stool, magnification lenses and both) using a portable surface electromyography (sEMG) device.

A New Management Technique for Symptomatic Haematomas Following Therapeutic Vacuum-Assisted Biopsy.

The aim of this study was to investigate the efficacy of the vacuum-assisted biopsy (VAB) system in evacuating symptomatic haematomas after VAB excision of benign breast lesions. We retrospectively analysed the data of eight patients with symptomatic and large haematomas who were treated with VAB evacuation between 10 and 14 days after VAB excision. Only one case underwent the procedure 24 h after VAB excision, due to the patient reporting intense pain, which was relieved after application of the technique, even though it had to be done twice.

Evaluation of rat liver with ARFI elastography: In vivo and ex vivo study.

Objective: The aim of this study was to compare in vivo vs ex vivo liver stiffness in rats with acoustic radiation force impulse (ARFI) elastography using the histological findings as the gold standard.

Methods: Eighteen male Wistar rats aged 16-18 months were divided into a control group (n = 6) and obese group (n = 12). Liver stiffness was measured with shear wave velocity (SWV) using the ARFI technique both in vivo and ex vivo.

Ultrasound-guided percutaneous electrolysis: A new therapeutic option for mammary fistulas.

Mammary fistula (MF) is a recurrent condition characterised by the draining of abscesses around the areola. The best management for MF remains challenging. Moreover, the main problem is the high recurrence rate of this disease.

Optimisation of sonourethrography: the clamp method.

Purpose: To describe the clamp method for performing retrograde sonourethrography (RSUG) and contrast-enhanced voiding sonourethrography (CE-VSUG) via the transperineal approach in male adults.

Materials And Methods: Prospective study of 113 males (14-86 years) with urethral strictures confirmed by urethrography who received sonourethrography via the clamp method between 2011 and 2015. The characteristic parameters of the quantitative variables were calculated and a comparative analysis of the qualitative variables was conducted using the McNemar test.

A new method for the prevention of skin laceration during vacuum-assisted breast biopsy.

Objective: To describe a new technique to prevent skin laceration during ultrasound-guided vacuum-assisted breast biopsy with the insertion of a spinal needle between the mass and the skin.

Methods: The study includes 118 patients with 118 breast imaging-reporting and data system Category 3 masses located very close to the skin or areola, which were excised using the mammotome system with a spinal needle inserted just above the site of insertion of the probe.

Results: The mean distance between the most superficial portion of the mass to the under surface of the overlying skin was 1.

Role of galactography in the early diagnosis of breast cancer.

Background: The purpose of this study was to evaluate the usefulness of galactography (GL) in the early diagnosis of breast cancer in patients with pathologic nipple discharge (PND).

Patients And Methods: We retrospectively studied all galactograms obtained in 117 women with PND, who subsequently had a biopsy. The findings detected in the galactograms of the patients in this study were assigned to different categories of the Galactogram Image Classification System (GICS): GICS 2, benign; GICS 3, probably benign; GICS 4, suspicious for malignancy; and GICS 5, highly suspicious for malignancy.

Efficacy of intralesional triamcinolone injection in the treatment of mammillary fistula: a prospective study.

Background: Recurring mammillary fistula (MF) is often difficult to manage.

Purpose: To evaluate the efficacy of intralesional triamcinolone (ILT) injection versus irrigation with saline solution in the management of MF.

Material And Methods: A prospective study was conducted including 10 patients with MF.

Sonographically guided percutaneous intralesional triamcinolone injection: a new treatment for mammillary fistulas: preliminary results.

We describe a new procedure, sonographically guided intralesional triamcinolone injection, for the treatment of mammillary fistulas. Six patients with mammillary fistulas were enrolled in this prospective study. Clinical improvement was rapid after the first triamcinolone injection.

An unusual case of locally advanced glycogen-rich clear cell carcinoma of the breast.

Glycogen-rich clear cell (GRCC) is a rare subtype of breast carcinoma characterized by carcinoma cells containing an optically clear cytoplasm and intracytoplasmic glycogen. We present the case of a 55-year-old woman with a palpable mass in the right breast and clinical signs of locally advanced breast cancer (LABC). The diagnosis of GRCC carcinoma was based on certain histopathological characteristics of the tumor and immunohistochemical analysis.

Follicular occlusion due to hyperkeratosis: a new hypothesis on the pathogenesis of mammillary fistula.

Mammary fistula (MF) is a disease characterised by recurrent draining abscesses around the areola. The aetiology of MF remains unclear. The most common cause is duct obstruction by squamous metaplasia.

Galactography: an application of the Galactogram Imaging Classification System (GICS).

Background: Galactography is the technique of choice for investigating pathological nipple discharge. However, there is no standardized interpretation system for this procedure.

Purpose: To evaluate radiological and histological correlation using a Galactogram Imaging Classification System (GICS).

Urethrography in men: conventional technique versus clamp method.

Purpose: To compare examination adequacy and patient discomfort during retrograde urethrography (RUG) performed by using the conventional balloon method versus those of RUG and voiding cystourethrography (VCUG) performed with the clamp method of using drip infusion for the administration of contrast material.

Materials And Methods: This prospective study was approved by the institutional review board; written informed consent was obtained from all patients. Eighty men (mean age, 64.

Use of urokinase in percutaneous drainage of large breast abscesses.

Objective: The purpose of this study was to evaluate intracavitary urokinase therapy versus irrigation with a saline solution in percutaneous drainage of large breast abscesses.

Methods: A prospective randomized study was conducted in 19 nonlactating women (median age, 35.7 years) with breast abscesses of greater than 3 cm.

A perfected device for performing retrograde urethrography.

The present study describes a perfected device for retrograde urethrography (RUG). The device allows RUG to be performed using a balloonless catheter and with assessment of the various problems of the urethra. The procedure is simple and well tolerated by patients and represents an interesting alternative to the conventional RUG technique.

Osteochondritis dissecans of the knee: sonographically guided percutaneous drilling.

Objective: The purpose of this study was to present a procedure for sonographically guided percutaneous drilling in the treatment of a case of osteochondritis dissecans (OD) of the knee.

Methods: A 14-year-old boy had OD of the external femoral condyle. Conventional radiography, magnetic resonance imaging, and sonography revealed the osteochondral lesion.

Ultrasound therapy in rectus sheath hematoma.

Background And Purpose: Ultrasound (US) is one of the most common modalities used in intervention for musculoskeletal disorders, although its effectiveness is debated. The purpose of this case report is to describe the intervention, including the use of US, in the management of a large rectus sheath hematoma (RSH) in a patient receiving anticoagulant therapy.

Case Description: The patient was a 62-year-old woman with RSH who was receiving oral anticoagulant therapy and had a history of bouts of coughing.