Sudden cardiac death in persons aged 50 years or younger: diagnostic yield of a regional molecular autopsy program using massive sequencing.

Introduction And Objectives: Sudden cardiac death (SCD) in young people often has a genetic cause. Consequently, the results of "molecular autopsy" may have important implications for their relatives. Our objective was to evaluate the diagnostic yield of a molecular autopsy program using next-generation sequencing.

Arteriosclerosis in paleopathology. Are macroscopic findings well known?

Although clinical atherosclerosis is fairly common, it is a surprisingly uncommon finding in anthropology. Several cases have been reported in the anthropological literature but most of them are referred to X-ray studies and to computerized tomographic imaging but, as far as we know, no macroscopic findings useful to anthropologists have been published before. We present a case of an adult male skeleton scattered on a wooded area with remains of partially mummified soft tissues between right tibia and fibula in which macroscopic findings showed a cylindrical structure that could be confused with a root or a branch.