Publications by authors named "Juan C Hernandez-Guerrero"

Background: Subgemmal neurogenous plaques (SNP) are composed of neural structures found in the posterolateral portion of the tongue, rarely biopsied as most of them are asymptomatic or eventually only clinically managed. We aimed to investigate a case series of possible correlation of symptomatic subgemmal neurogenous plaque (SNP) with coronavirus disease 2019 (COVID-19).

Methods: Eleven formalin-fixed paraffin-embedded cases from patients with previous confirmed COVID-19 (by RT-PCR) were retrieved from two pathology files.

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Article Synopsis
  • SARS-CoV-2, the virus responsible for COVID-19, can lead to a variety of symptoms, including fever, cough, and unique oral lesions, highlighting the need for early diagnosis.
  • A study examined 14 patients with oral lesions, aged 23 to 88, all confirmed to have COVID-19, with symptoms like dysgeusia and anosmia.
  • These lesions were classified into two types: ischemic/hemorrhagic and inflammatory, primarily affecting the palate and tongue, with evidence of viral presence in oral tissues.
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Salivary gland tumors (SGT) represent an uncommon heterogeneous group of tumors with complex clinical and pathological characteristics. The prevalence of these lesions varies between studies but has been estimated between 3 and 6% of all tumors in the head and neck region. The present study aimed to evaluate the distribution and demographic findings of salivary gland tumors diagnosed in an oral pathology service in Mexico.

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Article Synopsis
  • * The study reviewed eight cases of OAM from 2002 to 2019, primarily affecting men aged 33 to 77, most commonly in the gingiva and palate, with some patients showing cervical lymph node metastasis.
  • * The findings highlight the need for specific immunohistochemical tests to accurately diagnose OAM, as nearly all patients died from the disease within an average follow-up of 8.5 months.
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This study aims to evaluate the clinicopathological features, TNM status, AJCC staging and behavior of squamous cell carcinoma of the tongue (SCCT) in patients older than 45 years. The files of the Department of Pathology of the Hospital General de México were reviewed and all cases of SCCT in patients older than 45 years were selected. Clinicopathological features, treatment, follow-up, microscopic diagnosis, and IJCC and TNM staging were retrieved.

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Objectives: To test a more complete set of morphometric radiographic parameters to evaluate the idiopathic osteosclerosis (IO) lesions located in the maxillomandibular area and to know their features during routine radiographic evaluation.

Materials And Methods: Radiographs from patients attending the oral diagnosis clinic of our institution were reviewed. Evaluated parameters were gender and age of the patients, size, side, homogeneity, morphology, radiodensity, mineralization, borders, relation to roots, affected tooth or teeth and location of the analyzed lesions.

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Purpose: To assess radiographically the presence of an ossified stylohyoid complex (OSHC) with signs and symptoms of Eagle syndrome or other oro-facial painful diseases in patients attending our institution and to confirm that the important issue for study is to know the length of the ossificated portion of the stylohyoid complex only.

Methods: We separated 1000 consecutive files, and after selection, 922 panoramic radiographs were evaluated. Assessed parameters were gender and age of the patients, size, and location of the analyzed OSHCs.

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Introduction: Giant Osteosclerotic Lesions (GOLs) are a group of rarely reported intraosseous lesions. Their precise diagnosis is important since they can be confused with malignant neoplasms.

Objective: This retrospective study aimed to record and analyze the clinical and radiographic Giant Osteosclerotic Lesions (GOLs) detected in the maxillomandibular area of patients attending to our institution.

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Purpose: This office-based study was conducted to investigate the influence of an oral hygiene regimen, consisting of a stabilized stannous fluoride dentifrice and an advanced manual toothbrush, on gingival health and plaque accumulation in Mexican adults after 4 weeks of use.

Methods: This was an unsupervised, open-label, single-treatment, 4-week study conducted in Mexico. At Baseline, gingival health and plaque coverage were assessed for each participant by dentists using categorical scales.

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INTRODUCTION. Dental caries continues to affect a large percentage of Mexican children and currently advises that if diagnosed at an early stage can be reversed with minimally invasive treatments. The casein phosphopeptide amorphous calcium phosphate known as CPP-ACP is a phosphoprotein capable of releasing calcium and phosphate ions in the oral environment promoting remineralization.

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Objective: The purpose of this study was to evaluate caries and dental fluorosis among Mexican preschoolers and school-aged children in a non-endemic zone for fluorosis and to measure its biological indicators.

Methods: DMFT, DMFS, dmft, dmfs, and CDI indexes were applied. Fluoride urinary excretion and fluoride concentrations in home water, table salt, bottled water, bottled drinks, and toothpaste were determined.

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Objective: The assessment of urinary fluoride excretion during dental developing stage has been reported for different countries with community fluoride programs. Also, one of the factors that could influence on retention and excretion of fluoride is the deficient nutrition so the aim of this study was to determine fluoride urinary excretion by a group of preschool children with and without malnutrition.

Materials And Methods: Urinary samples from 24 hours were collected from 60 preschool children selected by convenience from Iztapalapa area of Mexico City, 30 with malnutrition and 30 with standard nutritrional status by weight for age.

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Objective: The aim of this study was to analyze table salt available in Mexico City's market to identify the fluoride concentrations and to compare these with the Mexican regulations.

Methods: We analyzed 44 different brands of table salt. All samples were purchased at random in different stores, supermarkets, and groceries from Mexico City's metropolitan area and analyzed in triplicate in three different laboratories (nine determinations per sample) with an Orion 720 A potentiometer and an Orion 9609 BN ion-specific electrode.

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Purpose: We present the clinicopathological findings after reviewing 52 patients affected by multifocal epithelial hyperplasia (MEH), previously known as focal epithelial hyperplasia and the results of an immunocytochemical study.

Patients And Methods: We reviewed the clinical files and microscopic slides from 52 MEH-affected patients and new slides were immunostained with a polyclonal antibody against high molecular weight cytokeratins.

Results: More than 95% of the patients were in poverty (<200 dollars monthly family income).

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Background: Despite that the role of inflammatory cells in chronic inflammatory reactions of pulpal origin (CIRPOs) has been extensively studied, function of the HLA-DR+ cells (HLA-DR+ Cs) is poorly understood. The aim of this study was to quantify their number and clarify their role in these lesions.

Methods: We studied 11 CIRPOs immunostained with an anti-HLA-DR class II monoclonal antibody and the number and location of the HLA-DR+ Cs quantified.

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Background: Ethanol consumption during pregnancy leads to changes in murine dental morphogenesis, dental size, cellular differentiation, enamel mineralization, and delayed eruption. It has been proposed that glycoproteins play a role during embryonic dental development that may determine the dental morphological pattern and extracellular matrix secretion. O-glycosylation and sialylation appear to actively participate in the differentiation and maturation processes.

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Background: Alcohol consumption during pregnancy can frequently lead to a congenital disorder known as fetal alcohol syndrome (FAS); however, not all children born to alcoholic women develop FAS. Alcohol consumption may affect diverse organs and systems during embryonic development, including craniofacial structures. Small teeth, enamel alterations, and delayed eruption have been observed after ethanol exposure.

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The role of mast cells (MCs) in periapical inflammatory lesions is not well understood. The objective of this work was to quantify MC numbers in human periapical lesions with the aim to clarify their role in the pathogenesis of these lesions. We analyzed the slides of 64 human periapical inflammatory lesions stained with pH 8.

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Unlabelled: This study was conducted to determine prevalence and severity of dental fluorosis and dental caries in school-children living in two zones of the Mexico City's East Area.

Methods: Fluorosis and caries scores were recorded for 1,569 children according to the Dean Community Index, DMFT and DMFS indexes, and the relationship between fluorosis and fluoride sources was investigated.

Results: Dental fluorosis was found in 60.

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The ultrastructure of human tooth enamel from a patient diagnosed to have amelogenesis imperfecta (AI) was investigated using atomic force microscopy (AFM) and compared with normal human tooth enamel. AI is a hereditary defect of dental enamel in which the enamel is deficient in either quality or quantity. Tissue-specific proteins, especially amelogenins, have been postulated to play a central role in amelogenesis.

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