Publications by authors named "Juan Antonio Solon"
Poor TB treatment outcomes are observed in patients with type 2 diabetes mellitus (DM) comorbidity and glycemic control throughout treatment may play a role. The objective of this study was to investigate glycemic control longitudinally among Filipino adults undergoing TB treatment using mixed-effects linear and logistic regression. Analyses were conducted in 188 DM-TB patients out of 901 enrolled in the Starting Anti-TB Treatment (St-ATT) cohort, with a median baseline glycosylated hemoglobin (HbA1c) of 8.
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- The study investigates the financial impact of tuberculosis (TB) combined with diabetes (TB-DM) on patients and their households in the Philippines, a country with high TB rates and diabetes prevalence.
- Data was collected over multiple points during treatment, looking at costs, income, and coping strategies among affected households in Negros Occidental and Cebu.
- Results showed that while TB-DM patients required more frequent medical visits, both TB-DM and TB-only patients faced similar rates of catastrophic costs, indicating that having diabetes does not significantly increase the financial burden from TB.*
Background: Rice fortification with vitamins and minerals has the potential to increase the nutrition in rice-consuming countries where micronutrient deficiencies exist. Globally, 490 million metric tonnes of rice are consumed annually. It is the dominant staple food crop of around three billion people.
View Article and Find Full Text PDFBackground: Vitamin A deficiency is a significant public health problem in many low- and middle-income countries, especially affecting young children, women of reproductive age, and pregnant women. Fortification of staple foods with vitamin A has been used to increase vitamin A consumption among these groups.
Objectives: To assess the effects of fortifying staple foods with vitamin A for reducing vitamin A deficiency and improving health-related outcomes in the general population older than two years of age.
Article Synopsis
- A Phase II study evaluated different formulations of a candidate tuberculosis vaccine (M72) combined with various doses of the AS01 Adjuvant System to find the lowest effective dose that is safe and induces strong immune responses.
- The study involved healthy adults in The Philippines, who received different vaccine combinations and were monitored for six months to assess their immune responses and safety.
- Results showed all vaccine formulations were safe, with the lowest dose of M72/AS01E (10 μg) demonstrating significant immune responses, leading to its selection for further development.
Background: Animal and human infection with multiple parasite species is the norm rather than the exception, and empirical studies and animal models have provided evidence for a diverse range of interactions among parasites. We demonstrate how an optimal control strategy should be tailored to the pathogen community and tempered by species-level knowledge of drug sensitivity with use of a simple epidemiological model of gastro-intestinal nematodes.
Methods: We construct a fully mechanistic model of macroparasite co-infection and use it to explore a range of control scenarios involving chemotherapy as well as improvements to sanitation.
Schistosomiasis affects 28 provinces in the Philippines found along the southeastern part where there is continuous rainfall throughout the year. In 2002 and 2005 respectively, two new endemic foci were reported in the northernmost (Gonzaga, Cagayan) and central (Calatrava, Negros Occidental) parts of the country. This study conducted in March 2008-March 2009 confirmed the presence of the disease by determining its prevalence using four diagnostic tests - Kato-Katz, circumoval precipitin test (COPT), ELISA and ultrasonography.
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