Automatic Multi-Atlas Liver Segmentation and Couinaud Classification from CT Volumes.

Primary Live Cancer (PLC) is the sixth most common cancer worldwide and its occurrence predominates in patients with chronic liver diseases and other risk factors like hepatitis B and C. Treatment of PLC and malignant liver tumors depend both in tumor characteristics and the functional status of the organ, thus must be individualized for each patient. Liver segmentation and classification according to Couinaud's classification is essential for computer-aided diagnosis and treatment planning, however, manual segmentation of the liver volume slice by slice can be a time-consuming and challenging task and it is highly dependent on the experience of the user.

Determination of Non-Invasive Biomarkers for the Assessment of Fibrosis, Steatosis and Hepatic Iron Overload by MR Image Analysis. A Pilot Study.

The reference diagnostic test of fibrosis, steatosis, and hepatic iron overload is liver biopsy, a clear invasive procedure. The main objective of this work was to propose HSA, or human serum albumin, as a biomarker for the assessment of fibrosis and to study non-invasive biomarkers for the assessment of steatosis and hepatic iron overload by means of an MR image acquisition protocol. It was performed on a set of eight subjects to determine fibrosis, steatosis, and hepatic iron overload with four different MRI sequences.