Publications by authors named "Juan Antonio Barcia Albacar"
Article Synopsis
- - The study evaluated long-term outcomes for patients with lumbar spinal stenosis (LSS) who underwent two different surgical approaches: a tubular retractor method and a uniportal endoscopic method.
- - Results showed that both approaches improved patients' pain and disability scores over three years, but there were no significant differences between the two groups in terms of these improvements.
- - Notably, the endoscopic group experienced significantly less blood loss during surgery, suggesting it may be a safer option with fewer complications compared to the tubular approach.
Study Design: Multicenter, prospective, randomized, and double-blinded study.
Objectives: To compare tubular and endoscopic interlaminar approach.
Methods: Patients with lumbar spinal stenosis and neurogenic claudication of were randomized to tubular or endoscopic technique.
Scaffolds with aligned channels based on acrylate copolymers, which had previously demonstrated good compatibility with neural progenitor cells were studied as colonizable structures both in vitro with neural progenitor cells and in vivo, implanted without cells in two different locations, in the cortical plate of adult rat brains and close to the subventricular zone. In vitro, neuroprogenitors colonize the scaffold and differentiate into neurons and glia within its channels. When implanted in vivo immunohistochemical analysis by confocal microscopy for neural and endothelial cells markers demonstrated that the scaffolds maintained continuity with the surrounding neural tissue and were colonized by GFAP-positive cells and, in the case of scaffolds implanted in contact with the subventricular zone, by neurons.
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