Publications by authors named "Juan Alberto Ascacio Valdes"

DC, commonly known as hojasen or tarbush, is a medicinal plant used in arid regions due to its therapeutic properties, especially in the treatment of gastrointestinal disorders. This study aimed to assess the toxicity of a polyphenolic extract obtained from . This research involved both (hemolytic and brine shrimp assay) and tests (acute oral toxicity) to determine the safety profile of this extract.

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Grape pomace (GP), a by-product of wine production, contains bioactive polyphenols with potential health benefits. This study investigates the anti-inflammatory properties of a polyphenolic fraction derived from GP, obtained by ultrasound-microwave hybrid extraction and purified using ion-exchange chromatography. In the inflammation model, mice were divided into six groups: intact, carrageenan, indomethacin, and three GP polyphenols treatment groups.

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Article Synopsis
  • Pomegranate peel (PP) and coffee pulp (CP) are food industry by-products rich in polyphenolic compounds, which could help prevent environmental pollution while also offering health benefits.
  • Research focused on the antiproliferative and cytotoxic effects of polyphenols from PP, CP, and a 50-50 mixture against various cancer cell lines (HeLa, A549, MDA-MB) showed promising results, indicating potential cancer-fighting properties.
  • The study found that while PP and CP polyphenols were effective against specific cancer cells, they did not significantly affect normal Hek-293 cells, highlighting their potential therapeutic use in targeting certain cancers.
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Synthetic chemicals are mainly used for the control of fungal diseases in tomato, causing the phytopathogens to generate resistance to the chemical active ingredient, with a consequent risk to human health and the environment. The use of plant extracts is an option for the control of these diseases, which is why the main objective of this research was to study an alternative biocontrol strategy for the management of plant diseases caused by fungi through obtaining polyphenol extracts from mistletoe plants growing on three different tree species-mesquite (), cedar (), and oak (), which contain flavones, anthocyanins, and luteolin. The overall chemical structure of the obtained plant extracts was investigated by RP-HPLC-ESI-MS liquid chromatography.

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The objective of the present work was to optimize the extraction of phytochemicals from Jacq. by ultrasound-assisted extraction. Taguchi L9 orthogonal array was used to evaluate the factors solid/liquid ratio (1:8, 1:12, and 1:16), extraction time (10, 20, and 30 min), and ethanol concentration (0, 35, and 70%).

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Fungal secondary metabolites with antimicrobial properties are used for biological pest control. Their production is influenced by several factors as environment, host, and culture conditions. In the present work, the secondary metabolites from fermented extracts of Beauveria bassiana PQ2 were tested as antifungal agents against Gibberella moniliformis LIA.

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Procyanidins are an important group of bioactive molecules known for their benefits to human health. These compounds are promising in the treatment of chronic metabolic diseases such as cancer, diabetes, and cardiovascular disease, as they prevent cell damage related to oxidative stress. It is necessary to study effective extraction methods for the recovery of these components.

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Article Synopsis
  • The study analyzed the nutrient composition, minerals, polyphenolic compounds, and antioxidant properties of green bean, mesquite, and pea flours.
  • Different combinations of these legume flours with wheat flour were tested for making bread, focusing on their effects on composition, color, volume, and functional properties.
  • Mesquite flour stood out for its high fiber and polyphenol content, while pea and green bean flours boosted protein levels, suggesting these legume flours can enhance the nutrition of baked products.
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Article Synopsis
  • The text discusses a specific fungus used in agriculture for pest control, focusing on a new laboratory-scale bioreactor designed for its production.
  • This bioreactor simultaneously generates two important products: oosporein (an antifungal compound) and aerial conidia (infective spores).
  • Optimal air flow for effective production was found to be 2.5 L/min, yielding significant concentrations of both oosporein and spores after 168 hours of culturing.
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In Mexico, mistletoes have several applications in traditional medicine due to the great variety of compounds with biological activities that have not been characterized to date. The goals of the present study are to analyze the composition of minerals and phytochemical compounds in Mexican mistletoes and subs. qualitatively and quantitatively, identify the compounds using HPLC-MS, and assess the antimicrobial potential in phytopathogenic microorganism control.

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The present research focused on evaluating the antibacterial effect and the mechanism of action of partially purified fractions of an extract of . Furthermore, both its antioxidant capacity and composition were evaluated. The extract was fractionated by vacuum liquid chromatography.

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The influence of ultrasound-assisted extraction of phytochemicals from Kunth on the antioxidant capacity was investigated. The factors evaluated were: ultrasound extraction time (10, 20 and 30 min), ethanol concentration (0, 35, 70 %) and solid/liquid ratio (1:4, 1:8 and 1:12 g mL). The L (3) array was applied, and the DPPH scavenging capacity of treatments was evaluated to obtain optimal extraction conditions.

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Citrus wax is a waste generated during the purification process of the citrus essential oil. A lot of citrus wax wastes are globally produced, despite this, its composition and properties are not well known. Here we present comprehensive results proving the chemical composition and the physical properties of citrus wax.

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The aim of the present study was to perform a screening of extracts obtained from 15 medicinal plants using water (at 25 and 90 °C) or ethanol (at 25 °C), to bactericidal activity against cariogenic ATCC 25175, as well as to carry out the preliminary phytochemical characterization of the extracts and HPLC/MS assay for selected extracts. The extractions were carried out for 5 h at 400 rpm. Only five from 45 tested extracts were selected based on their antibacterial activity.

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Fungal hydrolysis of ellagitannins produces hexahydroxydiphenic acid, which is considered an intermediate molecule in ellagic acid release. Ellagic acid has important and desirable beneficial health properties. The aim of this work was to identify the effect of different sources of ellagitannins on the efficiency of ellagic acid release by Aspergillus niger.

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