I-LIFT (image-based laser-induced forward transfer) platform for manipulating encoded microparticles.

Encoded microparticles have great potential in small-volume multiplexed assays. It is important to link the micro-level assays to the macro-level by indexing and manipulating the microparticles to enhance their versatility. There are technologies to actively manipulate the encoded microparticles, but none is capable of directly manipulating the encoded microparticles with homogeneous physical properties.

Color-Coded Droplets and Microscopic Image Analysis for Multiplexed Antibiotic Susceptibility Testing.

Since the discovery of antibiotics, the emergence of antibiotic resistance has become a global issue that is threatening society. In the era of antibiotic resistance, finding the proper antibiotics through antibiotic susceptibility testing (AST) is crucial in clinical settings. However, the current clinical process of AST based on the broth microdilution test has limitations on scalability to expand the number of antibiotics that are tested with various concentrations.

A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing.

Wireless monitoring of the physio-biochemical information is becoming increasingly important for healthcare. In this work, we present a proof-of-concept hydrogel-based wireless biochemical sensing scheme utilizing ultrasound. The sensing system utilizes silica-nanoparticle embedded hydrogel deposited on a thin glass substrate, which presents two prominent interfaces for ultrasonic backscattering (tissue/glass and hydrogel/glass).

Untethered Actuation of Hybrid Hydrogel Gripper via Ultrasound.

Stimuli-responsive hydrogels that exhibit reversible volume changes in response to stimulus cues such as heat, pH, and light have been utilized in soft robotics, microfluidics, electronics, and biomedical surgical tools. While the development of the soft robotics has widely expanded, most external triggering systems still have limited utilities due to the low selectivity. We present a hybrid gripper capable of undergoing preprogrammed shape transformation utilizing ultrasound energy on-off processes as the external triggering system, which can be utilized in invisible and nonselective environments.

Ultrasonic Hydrogel Biochemical Sensor System.

In this work, we present a proof-of-concept hydrogel-based sensor system capable of wireless biochemical sensing through measuring backscattered ultrasound. The system consists of silica-nanoparticle embedded hydrogel deposited on a thin glass substrate, presenting two interfaces for backscattering (tissue/hydrogel and hydrogel/glass), which allows for system output to be invariant under the change in acoustic properties (e.g.