Publications by authors named "Ju-Ying Tang"
Article Synopsis
- The study investigates serum steroid profiling as a potential tool to differentiate between malignant adrenocortical carcinoma (ACC) and benign adrenocortical adenomas (ACA), focusing on multiple steroid hormones in relation to tumor characteristics and patient demographics.
- Researchers analyzed data from 31 patients with ACC and 31 matched patients with ACA, finding that ACC patients had notably larger tumors, lower BMI, and significantly higher serum levels of certain steroids, particularly 11-deoxycortisol, which emerged as a key discriminative marker.
- The study concluded that serum steroid levels, especially 11-deoxycortisol, provide valuable insights for distinguishing ACC from ACA, suggesting a more nuanced approach beyond
Patients with primary aldosteronism (PA) have an increased risk of target-organ damage (TOD), but whether metabolic syndrome (MetS) is more prevalent and contributes to TOD in PA patients remains unresolved. We aimed to evaluate the associations between MetS profiles and TOD in Chinese PA individuals. Metabolic parameters and pre-clinical TOD including left ventricular hypertrophy, estimated glomerular filtration, and microalbuminuria; insulin sensitivity or resistance; and islet β-cell function were assessed by the homeostasis models (HOMA-IR, HOMA-β) and the other surrogate indexes [composite insulin sensitivity index (ISI), modified β-cell function index (MBCI)] determined from the oral glucose tolerance test were compared in PA vs.
View Article and Find Full Text PDFObjective: To compare plasma concentrations of biomarkers of endothelial dysfunction between patients with primary aldosteronism (PA) and essential hypertension (EH), and to determine whether elevated levels of these biomarkers could predict development of early organ damage.
Methods: Thirty-six PA patients and 39 EH patients matched for age, sex, blood pressure and duration of hypertension were included in this study. Plasma levels of biomarkers reflecting endothelial dysfunction (von Willebrand factor, vWF; soluble intercellular adhesion molecule 1, sICAM-1; and oxidized low density lipoprotein, ox-LDL) were detected and compared between PA and EH patients.
[Effect of compound danshen dripping pill on arterial intima-media thickness in patients with newly diagnosed type 2 diabetes mellitus].
Zhongguo Zhong Xi Yi Jie He Za Zhi
December 2010
Objective: To investigate the effect of compound Danshen Dripping Pill (CDDP) on peripheral arterial intima-media thickness (IMT) in patients newly diagnosed as type 2 diabetes mellitus.
Methods: One hundred and eight patients were equally randomized into 3 groups, in addition to the basic hypoglycemic, hypotensive and lipid-regulation treatment, they were administered orally with aspirin (0.1 g, once daily), vitamin E (0.