Publications by authors named "Ju Yeon Sim"
Article Synopsis
- Psychological stress and intestinal leakage play significant roles in the worsening of atopic dermatitis and its recurrence, as demonstrated in a study using AD mice.
- The study found that immobilization stress led to increased scratching, colon damage, and higher levels of stress hormones and toxins in the bloodstream, indicating a breakdown of the intestinal barrier.
- Treatment with antibiotics or intestinal permeability blockers helped reduce the stress-induced itching, but it could be re-triggered by injecting certain toxins, highlighting the involvement of gut bacteria and TLR4 signaling in the itch response.
