Publications by authors named "Ju Eun Kim"

Article Synopsis
  • - The study investigates the outcomes of biportal endoscopic lumbar interbody fusion (BELIF) in both primary and revision surgeries, reporting no significant differences in clinical improvements or fusion rates between the two groups.
  • - A total of 72 patients were followed for at least two years, assessing factors like disability index, pain levels, and hospital stays, with findings indicating longer surgery times and higher durotomy (spinal tears) rates for revisions.
  • - Overall, while revision BELIF shows similar effectiveness to primary procedures, it comes with increased surgical time and risks, highlighting the complexities associated with revision surgeries.
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Study Design: Retrospective study.

Objective: This study compared the fusion and subsidence rate and clinical outcomes when using different-sized static PEEK cages in BE-TLIF.

Summary Of Background Data: Biportal endoscopic techniques for transforaminal lumbar interbody fusion (BE-TLIF) have been shown to have similar clinical and fusion outcomes with faster clinical recovery in comparison to tubular surgery.

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Article Synopsis
  • The gut microbiota plays a significant role in maintaining immune health and brain function, with emerging research linking it to cognitive decline and dementia in older adults.
  • The study explored the effects of a specific gut bacterium, Agathobaculum butyriciproducens SR79, on cognitive impairment in aged mice, using various behavioral tests to assess changes in cognitive performance.
  • Results indicated that SR79 improved cognitive function in aged mice without affecting other behaviors, and it influenced brain health by altering dendritic spines and reducing astrocyte activation, suggesting it could be a promising treatment for age-related cognitive decline.
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Post-thyroidectomy syndrome (PTS), characterized by voice issues after thyroidectomy without recurrent laryngeal nerve injury, was investigated in this study. The Voice Fatigue Index (VFI) and cepstral analysis were employed for subjective and objective voice evaluation. Retrospective analysis involved 96 patients (37 males, 59 females) who underwent thyroidectomy without nerve injury from April 2018 to June 2022.

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Article Synopsis
  • - This study investigates the sociocultural factors affecting nursing research in a clinical setting at a Korean tertiary hospital, highlighting challenges that nurses face in utilizing research findings due to a lack of a positive research culture.
  • - Through participant observation and interviews with 6 registered nurses, the research reveals a central theme of fostering a growth-oriented environment in clinical practice, which includes balancing influences on the research process and enhancing communication among nurses.
  • - The findings emphasize the need for a supportive clinical research culture that harmonizes patient-centric research with the realities of nursing workloads, underscoring the importance of collaborative efforts among researchers, patients, and hospitals for effective research utilization.
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Background: Transforaminal lumbar interbody fusion with biportal endoscopic guidance (BE-TLIF) has been previously reported with promising clinical results. However, complications such as delayed union or subsidence occurred as with open surgery. We assumed using larger cages would result in less occurrence of such complications.

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Inotodiol, an oxysterol found only in Chaga mushroom, has received attention from the pharmaceutical industry due to its strong antioxidant and anti-allergic activities. However, the production of inotodiol is still challenging, and its fundamental properties have yet to be investigated. This study aims to develop an efficient method to produce high-purity inotodiol from Chaga mushroom.

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This study investigates the interactive effects of dietary illite and probiotic on productive performance, intestinal microflora, and blood profiles of laying hens. A total of 432 laying hens at 24 weeks old were allotted into six dietary groups. An experimental design was composed with a 3 (illite levels: 0, 0.

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Herpetic anterior uveitis-associated ocular inflammation is commonly manifested with ocular hypertension and glaucoma. Relative to other viruses, cytomegalovirus (CMV) positive hypertensive anterior uveitis is associated with high recurrences of uveitis, as well as with uncontrolled intraocular pressure (IOP) and a subsequent higher requirement for future glaucoma surgery. To gain novel insights into the pathogenesis of ocular hypertension in these patients, we investigated the proteome changes of the aqueous humor (AH) derived from the CMV hypertensive anterior uveitis (CMV-HAU; = 10) patients and non-glaucoma (cataract; = 10) patients using liquid chromatography with tandem mass spectrometry.

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In the biological microenvironment, cells are surrounded by an extracellular matrix (ECM), with which they dynamically interact during various biological processes. Specifically, the physical and chemical properties of the ECM work cooperatively to influence the behavior and fate of cells directly and indirectly, which invokes various physiological responses in the body. Hence, efficient strategies to modulate cellular responses for a specific purpose have become important for various scientific fields such as biology, pharmacy, and medicine.

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Vaccines are one of the most important strategies against pandemics or epidemics involving infectious diseases. With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there have been global efforts for rapid development of coronavirus disease 2019 (COVID-19) vaccine and vaccination is being performed globally on a massive scale. With rapid increase in vaccination, rare adverse events have been reported.

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Severe fever with thrombocytopenia syndrome (SFTS) is a new tick-borne viral disease, and most SFTS virus (SFTSV) infections occur bites from the tick ; however, SFTSV transmission can also occur through close contact with an infected patient. SFTS is characterized by acute high fever, thrombocytopenia, leukopenia, elevated serum hepatic enzyme levels, gastrointestinal symptoms, and multiorgan failure and has a 16.2 to 30% mortality rate.

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Uveitis caused by herpes simplex virus (HSV)-1 is characterized by increased intraocular pressure (IOP) in the presence of anterior chamber inflammation. Despite their clinical significance, the pathogenic changes associated with HSV-1 infection in trabecular meshwork (TM) cells, the key cell type regulating IOP, have not been completely elucidated. In this study, cytokine array analyses showed a significant stepwise increase in monocyte chemoattractant protein (MCP)-1 expression upon HSV-1 infection in TM cells (p < 0.

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The inflammatory chemokines, monocyte chemoattractant protein (MCP)-1 and IL-8, are produced by normal trabecular meshwork cells (TM) and elevated in the aqueous humor of primary open angle glaucoma (POAG) and hypertensive anterior uveitis associated with viral infection. However, their role in TM cells and aqueous humor outflow remains unclear. Here, we explored the possible involvement of MCP-1 and IL-8 in the physiology of TM cells in the context of aqueous outflow, and the viral anterior uveitis.

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Article Synopsis
  • The study explores the link between adenotonsillar issues and dysphonia in children, aiming to assess how tonsillectomy and adenoidectomy (T & A) affect voice quality post-surgery.
  • Out of 1,197 pediatric patients, 7.6% exhibited dysphonia pre-surgery, and follow-up showed significant improvements in voice quality indicators one and three months after T & A.
  • The findings suggest that T & A can lead to noticeable voice improvements, and maintaining good vocal hygiene may further enhance outcomes for children with dysphonia.
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Islet cell transplantation has been an effective method for the treatment of type 1 diabetes. The transplanted islets release insulin in response to changes in blood glucose levels. The clinical application of islet transplantation, however, has been hindered because of some critical problems including immune responses to grafted islets and side effects caused by overdosed immunosuppressive drugs.

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Study Design: Retrospective study.

Objective: The authors aimed to compare the clinical outcomes of biportal endoscopic transforaminal lumbar interbody fusion (BE-TLIF) with those of minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) using a microscope.

Summary Of Background Data: Lumbar spinal fusion has been widely performed for various lumbar spinal pathologies.

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Interbody fusion is a common surgical technique for diseases of the lumbar spine. Biportal endoscopic-assisted lumbar interbody fusion (BE-LIF) is a novel minimally invasive technique that has a long learning curve, which can be a barrier for surgeons. Therefore, we analyzed the learning curve in terms of operative time and evaluated the outcomes of BE-LIF.

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Magnetic tunneling junction (MTJ) materials such as CoFeB, Co, Pt, MgO, and the hard mask material such as W and TiN were etched with a reactive ion beam etching (RIBE) system using H/NH. By using gas mixtures of H and NH, especially with the H/NH( 2:1) ratio, higher etch rates of MTJ related materials and higher etch selectivities over mask materials (>30) could be observed compared to those etching using pure H( no etching) and NH. In addition, no significant chemical and physical damages were observed on etched magnetic materials surfaces and, for CoPt and MTJ nanoscale patterns etched by the H/NH( 2:1) ion beam, highly anisotropic etch profiles >83° with no sidewall redeposition could be observed.

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Etch characteristics of ovonic threshold switch (OTS) materials composed of Ge-As-Te for a phase-change random access memory (PCRAM) has been investigated using reactive ion etching hydrogen-based gases such as H, CH, NH, CH + H, and CH + NH. Among the investigated hydrogen-based gases, NH showed the highest etching rate of about 0.52 nm s, but the formation of nitride compounds and the increased roughness were observed on the OTS surface by nitrogen.

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Study Design: A prospective study.

Objective: To evaluate the change in cervical epidural pressure (CEP) during biportal endoscopic lumbar discectomy (BELD).

Summary Of Background Data: In percutaneous uniportal endoscopic lumbar discectomy, irrigation fluid (IF) introduced into the spinal canal during surgery can compress the thecal sac, and act as a potential risk for neurological complications by disturbing cerebrospinal fluid (CSF) circulation and increasing intracranial pressure.

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Background: Symptomatic postoperative spinal epidural hematoma (PSEH) is a devastating complication that could develop after lumbar decompression surgery. PSEH can also develop after biportal endoscopic spine surgery (BESS), one of the recently introduced minimally invasive spine surgery techniques. Gelatin-thrombin matrix sealant (GTMS) is commonly used to prevent PSEH.

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Study Design: Here we perform a retrospective analysis regarding an incidental dural tear (IDT) during biportal endoscopic spinal surgery (BESS).

Purpose: This study investigates the causes of IDT specifically related to technical procedures of BESS with the aim of lowering its risk during training.

Overview Of Literature: The incidence of dural tear is reported 0.

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Background: Biportal endoscopic spinal surgery (BESS) was recently introduced and became prevalent fast. Incidental dural tear (IDT) could happen as one of the common complications even in endoscopic spine surgery.

Case Description: A 45-year old male underwent discectomy by BESS.

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