A multitude of tools now exist that allow us to precisely manipulate the human genome in a myriad of different ways. However, successful delivery of these tools to the cells of human patients remains a major barrier to their clinical implementation. Here we introduce a new cellular approach for genetic engineering, ecreted article nformation ransfer (SPIT) that utilizes human cells as delivery vectors for genetic engineering.
View Article and Find Full Text PDFA multitude of tools now exist that allow us to precisely manipulate the human genome in a myriad of different ways. However, successful delivery of these tools to the cells of human patients remains a major barrier to their clinical implementation. Here we introduce a new cellular approach for genetic engineering, ecreted article nformation ransfer (SPIT) that utilizes human cells as delivery vectors for genetic engineering.
View Article and Find Full Text PDF