Publications by authors named "Joycenea da Silva Matsuda"
Single-Nucleotide Variants in the AIM2 - Absent in Melanoma 2 Gene (rs1103577) Associated With Protection for Tuberculosis.
Mariana Brasil de Andrade Figueira Dhêmerson Souza de Lima Antonio Luiz Boechat Milton Gomes do Nascimento Filho Irineide Assumpção Antunes Joycenéa da Silva Matsuda
Front Immunol
June 2021
Article Synopsis
- * The study investigated single-nucleotide variants (SNVs) in specific inflammasome genes in patients with pulmonary TB (PTB), extrapulmonary TB (EPTB), and healthy controls to understand their role in immune responses.
- * Results showed that SNV rs1103577 may offer protection against PTB, while rs1692816 reduces the risk for EPTB, highlighting the need for further investigation into their impact on immune responses, especially concerning IL
Article Synopsis
- - The study focuses on the prevalence and characteristics of pulmonary mycoses in patients who have smear-negative tuberculosis in the Brazilian Amazon.
- - Conducted at two tuberculosis reference institutions, the study analyzed 213 patients using various diagnostic methods and found that 7% were diagnosed with pulmonary mycoses, particularly aspergillosis and paracoccidioidomycosis.
- - A significant number of patients with pulmonary mycoses were former tuberculosis sufferers, with common symptoms including chronic cough and lung cavitation injuries.
The occurrence of tuberculosis with first-line multidrug resistance leads to the use of alternative medications, often at higher costs, longer treatment periods, and greater clinical complexity. Here, we report 3 patients with multidrug-resistant tuberculosis. One patient with human immunodeficiency virus died before the sensitivity test was performed.
View Article and Find Full Text PDF