Publications by authors named "Joyce W M Van Bree"

Article Synopsis
  • Vector-borne diseases, like those spread by mosquitoes, make up over 17% of infectious diseases around the world and may increase due to climate change.
  • Many mosquito-borne viruses (called arboviruses) can seriously harm humans and animals, with some causing major health issues.
  • Although there are a few vaccines for these viruses, most don’t have any, but scientists are working on new vaccine strategies that could help protect both people and animals from these diseases.
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Usutu virus (USUV) is a mosquito-borne flavivirus of African origin. Over the past decades, USUV has spread through Europe causing mass die-offs among multiple bird species. The natural transmission cycle of USUV involves .

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Hookworm infections cause a neglected tropical disease (NTD) affecting ~740 million people worldwide, principally those living in disadvantaged communities. Infections can cause high morbidity due to their impact on nutrient uptake and their need to feed on host blood, resulting in a loss of iron and protein, which can lead to severe anaemia and impaired cognitive development in children. Currently, only one drug, albendazole is efficient to treat hookworm infection and the scientific community fears the rise of resistant strains.

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Zika virus (ZIKV) is an arthropod-borne flavivirus predominantly transmitted by mosquitoes and poses a global human health threat. All flaviviruses, including those that exclusively replicate in mosquitoes, produce a highly abundant, noncoding subgenomic flavivirus RNA (sfRNA) in infected cells, which implies an important function of sfRNA during mosquito infection. Currently, the role of sfRNA in flavivirus transmission by mosquitoes is not well understood.

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