Publications by authors named "Joyce Uchi Nyiro"

Article Synopsis
  • Rhinoviruses (RV) present in humans show a lot of genetic variation, but their behavior in different social environments is not well studied.
  • This research investigated RV dynamics in Kenya by examining genetic sequences from various settings, including households, a school, and health facilities, finding the highest diversity of RV types at the nationwide level.
  • The study underscores the importance of social structures in influencing RV dynamics and suggests that understanding these patterns can improve public health strategies, with future research focusing on whole-genome analysis for deeper insights.
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Respiratory viruses are primary agents of respiratory tract diseases. Knowledge on the types and frequency of respiratory viruses affecting school-children is important in determining the role of schools in transmission in the community and identifying targets for interventions. We conducted a one-year (term-time) surveillance of respiratory viruses in a rural primary school in Kilifi County, coastal Kenya between May 2017 and April 2018.

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Endemic and seasonally recurring respiratory viruses are a major cause of disease and death globally. The burden is particularly severe in developing countries. Improved understanding of the source of infection, pathways of spread and persistence in communities would be of benefit in devising intervention strategies.

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Background: The target group for severe respiratory syncytial virus (RSV) disease prevention is infants under 6 months of age. Vaccine boosting of antibody titres in pregnant mothers could protect these young infants from severe respiratory syncytial virus (RSV) associated disease. Quantifying protective levels of RSV-specific maternal antibody at birth would inform vaccine development.

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