Publications by authors named "Joyce Rajan"
J Assoc Physicians India
May 2009
Article Synopsis
- The study aimed to analyze the rates and reasons for changing initial antiretroviral treatment (ART) among HIV-infected adults in South India, focusing on predictors of treatment change.
- In a follow-up of 230 HIV-positive patients over 48 weeks, 39.6% experienced treatment changes due to drug toxicities, largely from certain NRTIs, with lactic acidosis, anemia, and peripheral neuropathy being the most common adverse effects.
- While the ART regimens showed effectiveness in reducing disease progression and mortality, the high incidence of toxicities highlights the need for safer treatment options as access to ART expands.
