Lower serum ceruloplasmin levels correlate with younger age of onset in Parkinson's disease.

Ceruloplasmin functions as a ferroxidase in iron metabolism. Parkinson's disease (PD) is characterized by an increase in brain iron. We postulated that lower circulating ceruloplasmin levels in PD would result in rapid brain iron accumulation and an earlier age of onset.

Psychological or physiological: why are tetraplegic patients content?

Objective: To assess the effects of spinal cord injury (SCI) on perceived health-related quality of life (QOL).

Background: SCI is physically disabling, socially handicapping, and romantically limiting. Nevertheless, little is known about post-SCI neurocognitive and psychosocial life.