Publications by authors named "Joyce Donohue"

Potable water can be a source of transmission for legionellosis and nontuberculous mycobacterium (NTM) infections and diseases. Legionellosis is caused largely by , specifically serogroup 1 (Sg1). , , and are three leading species associated with pulmonary NTM disease.

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Strontium (Sr) is a natural element, ubiquitous in the environment and known to occur in water, food, air, and soils. Strontium is present in media as a salt or an ionized divalent cation. The Sr ion (dissociated) is toxicokinetically important because it is easily absorbed into systemic circulation when inhaled with particulates or ingested with water or foods.

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Article Synopsis
  • - The study focused on measuring 17 per- and polyfluoroalkyl substances (PFAS) in source and treated water from 25 drinking water treatment plants (DWTPs) across the U.S. to assess contaminants of emerging concern (CECs).
  • - PFAS were found in all 50 water samples, with a broad range of concentrations; the median total PFAS concentration was slightly lower in treated water (19.5 ng/L) compared to source water (21.4 ng/L).
  • - One DWTP exceeded the U.S. EPA’s health advisory level for PFOA and PFOS, and specific PFAS profiles were identified in plants along two major rivers, showing different dominant PFAS compounds
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Nontuberculous mycobacteria (NTMs) are environmental microorganisms that can cause infections in humans, primarily in the lung and soft tissue. The prevalence of NTM-associated diseases is increasing in the United States. Exposure to NTMs occurs primarily through human interactions with water (especially aerosolized).

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This article addresses the content of the workshop, including a panel discussion relevant to delineation of a path forward in relation to risk assessment of essential metals. The state of the art of risk assessment and associated issues for essential metals are outlined initially, followed by brief illustration by the case studies considered at the workshop (i.e.

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The Risk Assessment Work Group focused on six charge questions related to CHABS, cyanobacteria and their toxins. The charge questions covered the following topics: Research needed to reduce uncertainty in establishing health based guidelines. Research that minimize the cost and maximize the benefits of various regulatory approaches.

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The Health Advisory (HA) Program of the Office of Water provides informal technical guidance to Federal, State and local officials responsible for protecting health when emergency spills or contamination situations occur. Under this program, first initiated in 1985, HA values are developed for 1-day, 10-day, longer-term (approx. 7 years) and lifetime exposures based on data describing non- cancer endpoints of toxicity.

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