Publications by authors named "Joyce Barreto"
Background/objectives: This study investigates the metabolic profile of a single dose of etodolac in healthy volunteers, focusing on pharmacokinetics, clinical parameters, and metabolomic variations to identify biomarkers and pathways linked to drug response, efficacy, and safety.
Methods: Thirty-seven healthy volunteers, enrolled after rigorous health assessments, received a single dose of etodolac (Flancox 500 mg). Pharmacokinetic profiles were determined using tandem mass spectrometry analysis, and the metabolomic profiling was conducted using baseline samples (pre-dose) and samples at maximum drug concentration (post-dose) via liquid chromatography coupled with a quadrupole time-of-flight mass spectrometer.
Objective: This study aimed to analyze the relationship between the participation of professionals in simulation-based training and an increase in the rate of vaginal deliveries.
Methods: This retrospective observational study analyzed professionals' participation in high-fidelity simulation training during the pilot phase of the Appropriate Delivery Project, spanning from May 21, 2015 to May 21, 2016, along with the rates of vaginal deliveries across various hospitals. Data for participation by nurses and physicians were examined using a gamma distribution model to discern the predictors influencing the changes in the percentage of vaginal births.
Article Synopsis
- The study investigates the relationship between comprehensive lipid profiles assessed by mass spectrometry and traditional lipid measurements (like TAG and cholesterol) in adults with varying lipid conditions.
- It categorizes 128 adults into four groups based on their lipid profiles, including normolipidemic and various forms of dyslipidemia.
- Key findings show that dyslipidemic individuals have specific correlations between serum TAGs, cholesterol lipoproteins, and various lipid species, indicating distinct lipidomic signatures associated with different lipid disorders.
Detecting latent safety threats in an interprofessional training that combines in situ simulation with task training in an emergency department.
Adv Simul (Lond)
November 2018
Background: During in situ simulation, interprofessional care teams practice in an area where clinical care occurs. This study aimed to detect latent safety threats (LST) in a training program, which combined in situ simulation scenarios with just-in-time and just-in-place self-directed task training in an emergency department. We hypothesized this simulation-based training in actual care areas allows the detection of at least one LST per simulation scenario.
View Article and Find Full Text PDFFirst experience with multiple mini interview for medical school admission in Brazil: Does it work in a different cultural scenario?
Med Teach
October 2017
Purpose: Evaluation of non-cognitive skills never has been used in Brazil. This study aims to evaluate Multiple Mini Interviews (MMI) in the admission process of a School of Medicine in São Paulo, Brazil.
Methods: The population of the study comprised 240 applicants summoned for the interviews, and 96 raters.