Three dimensional model for the 16S ribosomal RNA in the Escherichia coli ribosome.

Molecular modeling has been performed to help correct and refine an approximate three dimensional structure for Eschericia coli 16S rRNA that originated as hand-built wire model. The wire model was built to accommodate the base pairs in 16S rRNA (1), mRNA.16S rRNA interactions (2,3), rRNA.

Identification and categorization of and cost for care of trauma patients: a study of 12 trauma centers and 43,219 statewide patients.

Medical and demographic data for trauma patients (n = 7120) admitted to 12 trauma centers in 1 year were reviewed. Data from New York State on all discharges for the same year (n = 2,535,501) were obtained and analyzed. Patients were identified as trauma patients based on NYC EMS trauma center advisory committee criteria translated into ICD-9-CM codes, and a computer-based algorithm was developed that identified 43,219 trauma patients.

An evaluation of a smoking prevention programme with children from disadvantaged communities.

This study examined the effect of a novel smoking prevention programme on children in primary schools in disadvantaged areas. The programme included integration with other school subjects as well as parental involvement and visits by Health Board personnel. Compared to matched control groups the classes in which the programme was piloted, showed less positive attitudes towards smoking and greater awareness of the dangerous consequences of smoking.

Dystonia in central pontine myelinolysis without evidence of extrapontine myelinolysis.

A 44-year-old female is described who developed persistent upper extremity and orolingual dystonia several weeks after suspected onset of central pontine myelinolysis (CPM), later confirmed by characteristic pontine lesions on MRI. No foci of the extrapontine myelinolysis were evident. This case confirms that dystonia may be a late and persistent sequela of CPM and may occur in the absence of visible lesions outside the brainstem.

Anti-inflammatory activiy of premna tomentosa willd. In albino rats.

An alcoholic extract of the leaves of Premna tomentosa Willd at a dose of 100 mg/kg body weight exhibited significant anti-inflammatory activity in albino rats. The extract caused reduction in the weight of spleen, thymus and adrenals. It reduced cotton pellet granuloma by 32.

Multicenter trial of gadoteridol, a nonionic gadolinium chelate, in patients with suspected head and neck pathology.

Purpose: To evaluate the safety and efficacy of gadoteridol as an MR contrast agent in patients with suspected head and neck pathology.

Methods: One hundred thirty-three adult patients were studied with MR at 12 clinical trial sites before and after the intravenous administration of 0.10 mmol/kg gadoteridol.

Perils and pitfalls of magnetic resonance imaging in the diagnosis of multiple sclerosis. The Rochester-Toronto MRI Study Group.

Purpose. Magnetic resonance imaging (MRI) has come to assume a position of major importance in the diagnostic process for multiple sclerosis (MS). The authors believe that a tendency toward overreliance on MRI results in isolation from clinical findings continues to result in both false-positive and false-negative diagnostic errors.

Multiple significant trauma diagnosis related groups: analysis and national projections based on the first year in an all-payor prospective payment system.

To assess the effect of diagnosis related group (DRG) changes on reimbursement for trauma care in New York State (NYS), 840 trauma patients were studied over a 2-year period. Average costs increased moderately ($10,338 vs. $11,646) while average revenues increased dramatically ($6,934 vs.

Antiinflammatory and antipyretic activity of vicolides of Vicoa indica DC.

Vicolides A,B, C and D, the sesquiterpene lactones isolated from V. indica exhibited antiinflammatory activity against cotton pellet granuloma in rats at dose level of 10 mg/kg body weight, sc. Highly significant activity was observed with vicolides C and D.

Studies on commercial saffron.

Two commercial samples of saffron were analysed for moisture and ash contents, solubility in water, action with sulphuric acid, presence of foreign dyes and colour intensity of water soluble solution.The moisture content in Laccha was 12.7% while it was 11% in Mogra.

An all-payor prospective payment system (PPS) based on diagnosis-related-groups (DRG): financial impact on reimbursement for trauma care and approaches to minimizing loss.

To assess the financial impact of the new all-payor prospective payment system (PPS), data for 430 patients admitted to a Level I Trauma Center were compared to all hospital discharges (n = 35,309). Trauma patients had a LOS of 13.1 days, average Trauma Score of 15, and operating loss for trauma patients totalled $1,310,625.

A comparison of default and reduced bandwidth MR imaging of the spine at 1.5 T.

The value of a reduced bandwidth MR imaging technique was tested prospectively in 51 spinal MR examinations by using default (16 kHz) bandwidth, 2000/30, 90 (TR/TEs) and 600/30, and reduced (8 kHz) bandwidth, 2000/48, 92 and 600/30, techniques at 1.5 T. Bandwidth reduction was used to maintain the signal-to-noise ratio for a reduced scan time.

Reduced-bandwidth MR imaging of the head at 1.5 T1.

A decrease in the magnetic resonance (MR) imaging bandwidth can be used to increase the signal-to-noise ratio (S/N) at constant imaging time or to maintain the S/N for reduction of imaging time. The effect of bandwidth reduction from the default value of 16 kHz to 8 kHz was evaluated prospectively in 50 patients referred for MR imaging of the head. On intermediate (2,000/30 [repetition time msec/echo time msec]) and more T2-weighted (2,000/90) studies, there were no definite missed diagnoses and no diagnostically important changes in lesion characteristics when the reduced-bandwidth technique was used to obtain half- or quarter-time studies, excluding differences attributable to unintentional changes in patient position between image acquisitions.

Emergency room visit time: changes over a 16-year period.

A one-week time and motion study was conducted at a large urban hospital replicating a study performed in 1969 in the same hospital, allowing a longitudinal study of emergency room utilization to be reported. Despite a 36% increase in the number of emergency room patients over the 16-year period, the findings from both studies replicate many of the patterns previously reported. Over time, both length of stay and wait times to see physicians have increased, although the values are still well within the ranges found in the literature.

Studies on the standardisation of mahalaksadi taila.

Malaksadi taila was prepared as per Ayurvedic formulary and was analysed. The specific gravity, saponification number, iodine number and acid number were 0.915, 199, 102 and 2 respectively.

Studies on mrtasanjivani sura.

Mrtasanjivani sura was prepared according to the formulary in an earthen pot and in a glass vessel. The drug fermented in glass vessel was distilled using glass joint distillation apparatus and that fermented in earthen pot was distilled by baka yantra method. The alcohol content in the finished medicine in the glass distilled and baka yantra methods were 3.

Comparative and fermentation stanardisationd studies on dasamularishta.

Asavas and arishtas are produced by fermentation in an earthen pot according to textual procedure. The size and shape of the pot and the quantity of the drug. That can be taken in a pot for fermentation is not mentioned in the literature.

Preparation of "777 oil" used for psoriasis in siddha medicine by modified method.

"777 oil" a coded drug of Siddha system of medicine was prepared and analyzed in the paper. The drug showed 3.62, 13.

Process and product standardisation of "77 oil" used for psoriasis in siddha medicine.

"777 oil" is a code drug of the Siddha system of medicine used in the treatment of Psoriasis. The drug is derived from the leaves Wrightia tinctoria by insolation, with coconut oil as base. The present study is aimed at comparing the drug prepared by insolation with that prepared in darkness.