Planning-to-binge: Time allocation for future media consumption.

The prevalence of streaming media has led firms to embrace the phenomenon of "binge-watching" by offering entire multipart series simultaneously. Such "on-demand" availability allows consumers to choose how to allocate viewing time, but such decisions have received little attention in the literature. Across several studies, we show that individuals can binging in advance by allocating time in ways that aggregate episode consumption.

Targeting tumour-associated macrophages in hodgkin lymphoma using engineered extracellular matrix-mimicking cryogels.

Tumour-associated macrophages are linked with poor prognosis and resistance to therapy in Hodgkin lymphoma; however, there are no suitable preclinical models to identify macrophage-targeting therapeutics. We used primary human tumours to guide the development of a mimetic cryogel, wherein Hodgkin (but not Non-Hodgkin) lymphoma cells promoted primary human macrophage invasion. In an invasion inhibitor screen, we identified five drug hits that significantly reduced tumour-associated macrophage invasion: marimastat, batimastat, AS1517499, ruxolitinib, and PD-169316.

Pelvic MRI staging of endometriosis at 3 T without patient preparation or anti-peristaltic: Diagnostic performance outcomes.

Purpose: Endometriosis is a disease of significant burden among pre-menopausal women characterised by the appearance of functional endometrial tissue in locations outside the uterus. Deep infiltrating endometriosis (DIE) is an invasion of the endometriotic lesion that exceeds 5 mm in depth into the peritoneum. In most cases, pelvic MRI is the imaging modality of choice for the pre-operative workup for DIE to guide surgery.

Learning Where to Look for High Value Improves Decision Making Asymmetrically.

Decision making in any brain is imperfect and costly in terms of time and energy. Operating under such constraints, an organism could be in a position to improve performance if an opportunity arose to exploit informative patterns in the environment being searched. Such an improvement of performance could entail both faster and more accurate (i.

Complications of laparoscopic adjustable gastric banding: our local experience.

Obesity is a major medical problem both within Australia as well as throughout the developed world. Achievement of weight loss for any individual patient brings an additional desirable benefit of improvement or resolution of a wide range of comorbid conditions. Bariatrics is the branch of medicine that deals with the causes, prevention and treatment of obesity and allied diseases.