Recruitment strategies for an osteoporosis clinical trial: analysis of effectiveness.

Aim: To examine the effectiveness of a planned rapid recruitment strategy in an osteoporosis clinical trial.

Methods: Multiple recruitment methods were explored, including media advertising, searching bone density scan and X-ray results in specialist and primary practice databases, community initiatives, and generation of research centre and study-specific pamphlets.

Results: Of 246 women screened, 41 consenting to the study, only 14 were randomised.

Atypical subtrochanteric fractures, bisphosphonates, blinded radiological review.

Background: Recent reports have suggested that a certain type of subtrochanteric and diaphyseal femoral fractures maybe associated with bisphosphonate (BP) therapy. We assessed the association between BP use in atypical and typical femoral fractures in a retrospective study and also looked at the rate of coding errors.

Methods: All cases between July 2003 and June 2008 with International Classification of Disease, 10th revision discharge codes for femoral fractures (S72.