Human blood groups in Dakahlya, Egypt.

New data on blood groups among Egyptians (Dakahlya province) are obtained by studying eight blood group systems: ABO, Rhesus, MNSs, Kell, Duffy, Kidd, P and Lewis. Comparing our results with the data reported in neighbouring countries, we found in Egypt a high frequency of B, NS, cDe and K genes, a moderately high frequency of P and the presence of Fy gene. The Egyptian population appears as a mixture of African, Asiatic and Arabian characteristics.

[Evaluation of erythrocyte survival by the determination of glycosylated hemoglobin. Clinical value].

In normoglycaemic subjects the haemoglobin glycosylation rate primarily depends on duration of erythrocyte life. Measurements of glycosylated haemoglobin therefore can be used to evaluate erythrocyte life. Indeed, glycosylated haemoglobin is significantly reduced (p less than 0.

Transplant of rhesus-positive bone marrow in a rhesus-negative woman having anti-rhesus D alloantibodies.

A woman affected by acute myeloblastic leukemia was grafted with HLA A, B and D compatible rhesus-positive bone marrow from her brother. Before grafting, she had anti-D alloantibodies (1/512 IAT, 2.9 micrograms/ml).

Improvement of enzyme-linked antiglobulin test by using an antiglobulin linked to glucose oxidase: description of the technique.

The classic enzyme-linked antiglobulin test (ELAT) used to detect and quantify the amount of IgG antibodies on red blood cells (RBC) is sensitive to hemolysis and erythrocyte enzymatic activities. We describe a new ELAT by using glucose oxidase (GO) linked to antihuman IgG. The optical density base line of GO-ELAT, alkaline phosphatase-ELAT and peroxidase-ELAT were, respectively, 0.

[Immunohemolytic complications observed during transfusion of more than 2 million units of blood].

From 1955 through 1978, 150 immunohemolytic accidents of variable gravity have been documented, representing an incidence of 7.1 cases out of 100 000 transfused blood units. These accidents can be classified as follows: 83 cases due to ABO incompatibility, 42 cases due to an irregular antibody in the recipient (six times due to anti-D), 20 cases induced by passive maternal antibodies in the newborn and 5 cases which were attributed to injected anti-A or anti-B antibodies.

[Erythrocyte phenotypes and gene frequency of the ABO system in the Congo population. Evaluation based on 5,400 subjects].

The purpose of this study is to determine the gene frequencies of the ABO blood groups in Congo where there is no data available. High frequency of O gene (0,7252 is noted. The frequency of gene A found to be close to the B gene's.

[Fetal death and benign hemolytic disease of the newborn from anti-Cellano alloimmunization: 2 new case reports].

The first case is provided by a french women (KK, husband k/k) who delivered a first healthy full term infant in 1970 and received one blood unit at this time. In 1972 and 1975, his second and fourth pregnancies ended by spontaneous abortion. In 1974 and 1976, she delivered stillborn infants with hydrops fetalis during the sixth month.

[Perinatal hemolytic disease due to incompatibility in the U system (author's transl)].

We report the case of a 3 week-old black infant who presented with hemolytic anemia due to an incompatibility with his mother in the U blood group system. Jaundice, present on the 3rd day of life, was considered as physiologic jaundice. A positive Coombs test led to the discovery in the mother's serum of an immune antibody against the U public antigen.

[Exclusion of MNSS, Kidd and Gm from the extreme end of the short portion of chromosome 8].

11 blood and seric group markers were studied in a case of 46,XX,del(8)(qter yields p22 :) in order to contribute to the exclusion map. MNSs and Jk are informative and could be excluded from the region. The proband is also definitly heterozygous for immunoglobulin Gm groups which were tentatively assigned to the short arm of chromosome 8 or 12.

[Changes in the erythrocyte membrane during blood preservation. Influence of progesterone].

Modifications of the erythrocyte membrane during blood conservation are studied. The functional condition of the membrane was observed by means of the biosynthesis of lecithines; modifications occurring at the level of the composition of the membrane proteins were then looked for. The study has been carried out on fresh blood and on blood stroed for 8 days, 15 days, 29 days and 43 days.

[Detection and prognostic significance of Ag "e" and its antibody in the course of HB virus infections[].

A new antigen antibody system the e Ag and Ab has been investigated by immunodiffusion and counterelectrophoresis in the serum of 509 subjects. Those included 242 patients with polyarteritis, acute chronic or fulminant hepatitis; 85 hemodialysis HBs Ag carriers and 182 asymptomatic HBs Ag carrier blood donors. Neither e Ag nor anti- e were detected in any of the non hepatitis B virus associated cases.

Alpha-Fetoprotein levels in normal males from seven ethnic groups with different hepatocellular carcinoma risks.

Alpha-Fetoprotein (AFP) levels of 1,335 males (15 years and older) of seven ethnic groups (Chinese, Indians, and Malays from Singapore, Caucasians from Lyon, and Blacks from Nairobi, forest, and the savanna region of the Ivory Coast) were determined by radioimmunoassay. A few elevated levels (up to 30 nanounits/ml) were detected in some normal individuals, especially in the older age-groups. In addition, there was a systematic age-dependency of AFP levels particularly evident in the groups from Singapore-Lyon, in which there was a 50% AFP increase between the ages of 20 and 40.