Publications by authors named "Joulia K Tsetis"

Introduction: The utilization of probiotics in enhancing the active healing of skin wounds represents a burgeoning trend in contemporary medicine. Previous research has extensively explored wound healing mechanisms involving the strains of , and . This study seeks to compare and interpret cellular findings derived from immunohistochemical and pathological applications.

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The skin serves as a critical barrier against external threats-dehydration, ultraviolet exposure, and infections-playing a significant role in internal homeostasis and moisture retention. Additionally, and equally importantly, it interacts dynamically with the complex microbiome resident in it, which is essential for maintaining skin health. Recent interest has focused on the use of probiotics and postbiotics, besides their ability to modulate the skin microbiome, to enhance barrier function, and exhibit anti-inflammatory properties, to be involved in skincare, by having the potential to improve skin hydration, elasticity, and overall appearance, as well as in reducing signs of aging, such as wrinkles and fine lines.

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Article Synopsis
  • Wound healing is a complex process aimed at repairing tissue damage, and recent studies suggest that topical application of probiotics can enhance this process.
  • Different probiotic strains may have unique effects on various healing phases, indicating that a combination of multiple strains could yield better outcomes than using a single strain.
  • This review aims to summarize the mechanisms of the most researched probiotic strains to aid in developing effective combinations for optimizing wound healing.
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Article Synopsis
  • Researchers used a standardized wound model and measured the mRNA expression of genes related to inflammation, healing, and blood vessel formation (angiogenesis) after applying the probiotics every two days.
  • Results showed that a combination of probiotics is more effective in promoting healing and angiogenesis compared to using them alone, suggesting that an ideal treatment should include multiple probiotic strains for better healing outcomes.
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Nowadays, there is an increasing knowledge that probiotic bacteria, topically applied, affects skin pathology. The objective of this study is to evaluate the effect on wound healing of locally applied probiotics by calculating the 3-D configuration of a standardized excisional wound. Fifty-two male Wistar rats were randomly allocated into groups: control, PRO1 [L.

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