Citric acid crosslinked hydroxyethyl tamarind gum-based hydrogel films: A promising biomaterial for drug delivery.

This investigation explored citric acid crosslinked hydroxyethyl tamarind gum hydrogel films as a potential biomaterial for drug delivery. Hydroxyethylation of tamarind gum aimed to improve its solubility, swelling, and crosslinking potential. The synthesized hydroxyethylated tamarind gum (HETG) was comprehensively characterized, revealing the presence of hydroxyethyl groups and increased viscosity in comparison to unmodified tamarind gum.

Synthesis and pharmacological screening of some novel anti-hypertensive agents possessing 5-Benzylidene-2-(phenylimino)-thiazolidin-4-one ring.

In the present study, fourteen derivatives comprising of 5-benzylidene-2-(phenylimino)-thiazolidin-4-one moiety were synthesized. The structures of synthesized compounds were established by elemental analysis, IR, (1)H NMR, (13)C NMR and mass spectral data and tested for electrocardiographic, antiarrhythmic and antihypertensive activities. Compound 11 was found to be most potent in this series.