Evaluation and correlation of the physicochemical properties of carvedilol.

Carvedilol is an antihypertensive drug with non-selective blockade (moderate selectivity for β1 and β2 adrenoceptors) and vasodilating properties due to α receptor blockade. Its molecule has one chiral centre; therefore, the drug has two enantiomers. Furthermore, it presents different polymorphs depending on the synthesis route and crystallization procedure.