Publications by authors named "Josje D Schoufour"

Article Synopsis
  • Accurate diagnosis of sarcopenia involves assessing muscle quality, specifically how much fat is infiltrated in muscle tissue, which is crucial for predicting mortality in TAVI patients.
  • The study analyzed CT scans from 1199 patients who underwent TAVI between 2010 and 2020, employing deep learning algorithms to measure skeletal muscle density (SMD) and intermuscular adipose tissue (IMAT).
  • Results indicated that low muscle quality, identified through both low SMD and high IMAT, significantly correlates with increased mortality risk, suggesting that muscle quality metrics are valuable predictors of health outcomes post-TAVI.
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Background: Sarcopenic obesity significantly burdens health and autonomy. Strategies to intervene in or prevent sarcopenic obesity generally focus on losing body fat and building or maintaining muscle mass and function. For a lifestyle intervention, it is important to consider psychological aspects such as behavioral change techniques (BCTs) to elicit a long-lasting behavioral change.

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Background: Chronic low-grade inflammatory profile (CLIP) is one of the pathways involved in type 2 diabetes (T2D). Currently, there is limited evidence for ameliorating effects of combined lifestyle interventions on CLIP in type 2 diabetes. We investigated whether a 13-week combined lifestyle intervention, using hypocaloric diet and resistance exercise plus high-intensity interval training with or without consumption of a protein drink, affected CLIP in older adults with T2D.

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Importance: Sarcopenia and obesity are 2 global concerns associated with adverse health outcomes in older people. Evidence on the population-based prevalence of the combination of sarcopenia with obesity (sarcopenic obesity [SO]) and its association with mortality are still limited.

Objective: To investigate the prevalence of sarcopenia and SO and their association with all-cause mortality.

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Background: Sarcopenic obesity (SO) is an increasing phenomenon and has been linked to several negative health consequences. The aim of this umbrella review is the assessment of effectiveness and certainty of evidence of nutrition and exercise interventions in persons with SO.

Method: We searched for meta-analyses of RCTs in PubMed, EMBASE and CENTRAL that had been conducted in the last five years, focusing on studies on the treatment and prevention of SO.

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Referral to home-based cardiac rehabilitation (HBCR) is low among older and frailer patients due to low expectations regarding adherence by healthcare professionals. The aim of this study was to determine adherence to HBCR when old and frail patients are referred, and to explore any differences in baseline characteristics between adherent and nonadherent patients. Data of the Cardiac Care Bridge were used (Dutch trial register NTR6316).

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The retirement phase is an opportunity to integrate healthy (nutrition/exercise) habits into daily life. We conducted this systematic review to assess which nutrition and exercise interventions most effectively improve body composition (fat/muscle mass), body mass index (BMI), and waist circumference (WC) in persons with obesity/overweight near retirement age (ages 55-70 y). We conducted a systematic review and network meta-analysis (NMA) of randomized controlled trials, searching 4 databases from their inception up to July 12, 2022.

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Article Synopsis
  • Older patients scheduled for heart procedures often don't follow dietary and activity guidelines, so this study looked into what helps or hinders them in making healthy changes pre-TAVI (transcatheter aortic valve implantation).
  • The research involved 13 patients aged around 82, who were interviewed and analyzed by two researchers, leading to the identification of barriers like low physical capability, lack of prioritization, and ingrained habits, as well as facilitators like knowledge about health benefits, social norms, and support from others.
  • The findings suggest that while many older patients see dietary and physical activity as low priorities, they may be willing to change if they understand the health benefits, indicating a need for healthcare professionals to use motivational interviewing techniques to help
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Article Synopsis
  • - The review examines the effectiveness of nutritional and exercise interventions in managing sarcopenic obesity in individuals aged 50 to 70 years, highlighting the potential of these strategies during retirement.
  • - A total of 11 randomized controlled trials were included after screening 261 studies, focusing on interventions lasting at least 8 weeks with community-dwelling participants.
  • - Meta-analysis revealed that resistance training significantly reduced body fat, increased muscle mass and strength, and slightly improved gait speed, while combined protein and exercise interventions also contributed to fat mass reduction.
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It is suggested that older patients waiting for an elective surgical procedure have a poor nutritional status and low physical activity level. It is unknown if this hypothesis is true and if these conditions improve after a medical procedure. We aimed to determine the trajectory of both conditions before and after transcatheter aortic valve implantation (TAVI).

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Article Synopsis
  • - Older patients undergoing transcatheter aortic valve implantation (TAVI) may still face issues like physical decline and increased mortality, even if the surgery is successful.
  • - A systematic review found that low muscle strength and poor physical performance (like slow walking speed or difficulty in mobility tests) were linked to higher long-term death rates after TAVI.
  • - The review highlighted the need for future studies to explore ways to improve muscle strength and physical performance in older patients to potentially enhance their outcomes post-surgery.
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Article Synopsis
  • Manual muscle mass assessment via CT scans helps identify malnutrition and sarcopenia, but the process is labor-intensive and needs a more efficient automated method.
  • This study involved 583 patients undergoing Transcatheter Aortic Valve Replacement (TAVR) to evaluate a deep learning-based method for automatically annotating psoas muscle areas, comparing it to manual analysis.
  • Results showed the automated method had good accuracy and reliability, indicating it could be a valuable tool for larger studies on muscle mass without the extensive time commitment of manual analysis.
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The aging population faces two conditions that threaten healthy aging: high fat mass (obesity) and low muscle mass and function (sarcopenia). The combination of both-referred to as sarcopenic obesity-synergistically increases the risk of adverse health outcomes. The two conditions often co-occur because they reinforce each other and share common etiologies, including poor nutrition and inactivity.

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Background: Across the world, frailty is part of the guidelines that are being developed in the COVID-19 pandemic for triaging in crisis situations. The Clinical Frailty Scale (CFS) evaluates the ability to perform daily tasks to identify frail individuals, potentially excluding those from intensive care (IC) treatment. Individuals with intellectual disabilities (ID) experience varying degrees of dependence, distinct from age-related physical deterioration.

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Sarcopenia is a heterogeneous skeletal muscle disorder involving the loss of muscle mass and function. However, the prevalence of sarcopenia based on the most recent definition remains to be determined in older people with chronic airway diseases. The aim was to evaluate sarcopenia prevalence and association with chronic airway diseases and its lung function in an older population, using the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria.

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Although there is some evidence that total dietary antioxidant capacity (TDAC) is inversely associated with the presence of obesity, no longitudinal studies have been performed investigating the effect of TDAC on comprehensive measures of body composition over time. In this study, we included 4595 middle-aged and elderly participants from the Rotterdam Study, a population-based cohort. We estimated TDAC among these individuals by calculating a ferric reducing ability of plasma (FRAP) score based on data from food-frequency questionnaires.

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Background: Since the placenta also has a sex, fetal sex-specific differences in the occurrence of placenta-mediated complications could exist.

Objective: To determine the association of fetal sex with multiple maternal pregnancy complications.

Search Strategy: Six electronic databases Ovid MEDLINE, EMBASE, Cochrane Central, Web-of-Science, PubMed, and Google Scholar were systematically searched to identify eligible studies.

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Purpose: To investigate the longitudinal association between the macronutrient composition of the diet and frailty.

Methods: Data were obtained from 5205 Dutch middle-aged and older adults participating in the Rotterdam Study. Frailty was measured using a frailty index based on the accumulation of 38 health-related deficits, score between 0 and 100, and a higher score indicating more frailty.

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COPD is associated with a progressive loss of muscle mass and function. However, there is an unmet need to define and standardise methods to estimate the prevalence of sarcopenia in COPD patients.We performed a systematic review and meta-analysis of the prevalence of this extrapulmonary manifestation in COPD patients.

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Increasing awareness of the impact of frailty on elderly people resulted in research focusing on factors that contribute to the development and persistence of frailty including nutrition and physical activity. Most effort so far has been spent on understanding the association between protein intake and the physical domain of frailty. Far less is known for other domains of frailty: cognition, mood, social health and comorbidity.

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Intake of individual antioxidants has been related to a lower risk of type 2 diabetes. However, the overall diet may contain many antioxidants with additive or synergistic effects. Therefore, we aimed to determine associations between total dietary antioxidant capacity and risk of type 2 diabetes, prediabetes and insulin resistance.

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Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide. Obesity is a major risk factor for NAFLD and recently, low skeletal muscle mass emerged as additional risk factor for NAFLD. However, the different contributions of body mass index (BMI) to the risk of NAFLD are not yet well-known.

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Purpose: To assess joint effects of genetic and modifiable factors on the 10-year progression of age-related macular degeneration (AMD).

Design: Individual and pooled data analyses of 2 population-based cohorts.

Participants: Blue Mountains Eye Study (BMES) and Rotterdam Study (RS) participants (n = 835).

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Background & Aims: High protein intake has been linked to increased type 2 diabetes (T2D) risk. However, if this association differs by protein from specific food sources, and if a habitual high protein intake affects insulin resistance and prediabetes risk are largely unknown. We aimed to investigate associations between protein intake from different food sources with longitudinal insulin resistance, and risk of prediabetes and T2D.

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Purpose: Several studies have reported seasonal variation in intake of food groups and certain nutrients. However, whether this could lead to a seasonal pattern of diet quality has not been addressed. We aimed to describe the seasonality of diet quality, and to examine the contribution of the food groups included in the dietary guidelines to this seasonality.

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