Publications by authors named "Josiano Guilherme Puhle"
Resistance physical exercise modulates metabolic adipokines, decreases body weight, and improves glomerular filtration in patients with chronic kidney disease in hemodialysis.
Mol Cell Biochem
October 2024
Article Synopsis
- * A study evaluated the impact of resistance exercise during hemodialysis on various health factors and found significant improvements in circulating irisin, handgrip strength, glomerular filtration rate, and reductions in body weight, adiponectin, glucose, and albumin levels.
- * Interestingly, vitamin D levels increased after the exercise program, and sex differences were noted, with females showing increased irisin levels while males exhibited differing results in strength and body weight.
Physical exercise as a modulator of the purinergic system in the control of sarcopenia in individuals with chronic kidney disease on hemodialysis.
Purinergic Signal
June 2024
The word sarcopenia derives from the Greek terms "sarx" for meat and "penia" for loss, thus being used to define reductions in muscle mass, muscle strength, and lower physical performance that compromise, mainly, the elderly population. Its high negative impact on patients' quality of life encourages the production and publication of new studies that seek to find methods to prevent and reverse cases of loss of muscle mass and strength. Furthermore, the high prevalence of sarcopenia in patients with chronic kidney disease (CKD) is closely related to its pathophysiology, which consists of a state of increased protein catabolism and decreased muscle tissue synthesis.
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- Respiratory infections, especially caused by viruses like SARS-CoV-2, have become the top infectious disease concern globally, with COVID-19 presenting serious health system challenges due to high morbidity and mortality rates.* -
- Factors affecting the immune response to COVID-19 include age, genetics, nutrition, and environment, but there is currently no specific treatment for the disease.* -
- This study highlights that regular moderate exercise and maintaining vitamin D levels can boost the immune system, reducing inflammation and helping to prevent complications such as the cytokine storm in COVID-19 patients.*
Digital image processing: a useful tool in the analysis of lung injuries caused by chronic inhalation of agricultural herbicides.
Environ Sci Pollut Res Int
November 2021
The herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) is widely used in agriculture to control various weeds. The objective of this study was to use the digital image processing method to identify alveolar lesions in the lungs of rats submitted to chronic 2,4-dichlorophenoxyacetic acid (2,4-D) inhalation exposure. We used forty adult male Wistar rats.
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