Publications by authors named "Josiane de Fatima Gaspari Dias"

Article Synopsis
  • * Studies on Symplocos tetrandra using light and scanning electron microscopy revealed key anatomical features, such as calcium oxalate crystals and specialized stomata, useful for species identification.
  • * The presence of these metabolites and unique anatomical markers indicates potential for further pharmacological research and taxonomic classification of S. tetrandra.
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The order Sapindales is comprised of nine families and in Brazil it is represented by six, including Rutaceae Juss., which constitutes the largest group of this order. A variety of species of Zanthoxylum L.

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Gabiroba, a native fruit in Brazil's Atlantic Forest region, has significant nutritional and therapeutic properties. However, due to its seasonality, consumption by the population is limited. Thus, the development of gabiroba byproducts would add significant value to the food and therapeutic industries.

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Viral diseases are the cause of many global epidemics, leading to deaths, affecting the quality of life of populations, and impairing public health. The limitations in the treatment of viral diseases and the constant resistance to conventional antiviral treatments encourage researchers to discover new compounds. In this perspective, this literature review presents isolated molecules and extracts of natural products capable of inhibiting the activity of the nonstructural protein that acts as the RNA-dependent RNA polymerase.

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This article describes the morpho-anatomies of the leaves and stems of Ocotea paranaensis Brotto, Baitello, Cervi & Santos (Lauraceae) using light and scanning electron microscopy. The main anatomical features characterizing the species are the presence of simple non-glandular trichomes in the leaves and stems, large secretory cells in the leaves, flat-convex petioles with two small lateral ribs, brachysclereids in the stem cortex and pith, and the presence of starch grains and various types of calcium oxalate crystals in the pith. Histochemical tests indicated the presence of lignin in stone cells, fibers, and xylem.

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The genus exhibits a variety of pharmacological, antibacterial and antioxidant effects. The aim of the present study was to evaluate the antioxidant potential and antibacterial properties of the ethyl acetate fraction of leaves. Isolation and identification of the phenolic compounds from the fraction was also carried out.

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Introduction: Aedes aegypti is the main vector of dengue and yellow fever. Recently, the use of plant-sourced larvicides has gained momentum.

Methods: The hydroethanolic extracts and fractions ofOcotea nutansleaves and stems were bioassayed to determine the larvicidal efficacy of these samples.

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Studies have demonstrated that diet rich in cruciferous vegetables of the Brassicaceae family can reduce the risk of cardiovascular diseases and oxidative stress levels. Nasturtium officinale (Brassicaceae), commonly known as watercress is a perennial dicotyledonous plant usually found close to water. Although previous investigations have demonstrated the beneficial effects of watercress on hypercholesterolemia in animal studies, until now no such studies have been conducted with humans, up to this time.

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The growing interest in the discovery of new compounds from medicinal plants justifies the study of phytochemical components of these plants and their biological activities. The genus exhibits a variety of pharmacological, antimicrobial and antioxidant effects. The aim of the present study was to evaluate the antioxidant potential and antimicrobial properties of the ethyl acetate fraction of leaves.

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Natural products, especially plants, have been investigated as sources of new substances with antimicrobial properties. In this context, the genus is extensively researched for presenting such activities. This work aims to evaluate the antifungal, antibacterial, and antioxidant properties of extracts and fractions of stems of , also to characterize two phenolic compounds.

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Several essential oils have allelochemicals with phytotoxic effects. species are producers of secondary metabolites with biological potential. In the present study, chemical composition of the essential oil extracted from aerial parts of Linnaeus was evaluated by gas chromatography and the phytotoxicity of the oil on seeds was evaluated for the first time.

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The aim of this work is to develop a W/O/W multiple emulsion with gallic acid in the internal aqueous phase (W). A quantification method for gallic acid using HPLC-UV was developed and validated. In the first step, a simple W/O emulsion was prepared with distilled water, polyglycerol polyricinoleate, sodium chloride, gallic acid and pH 5.

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Bixin is the main natural apocarotenoid extracted from the seeds of widely used as a cosmetic and textile colorant. Despite the description of several pharmacological properties of extracts, little has been studied regarding the pharmacological properties of bixin. Then we aimed to investigate the potential anti-inflammatory and antinociceptive effect of bixin in preclinical models of inflammation and acute pain.

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The Lauraceae family is predominantly found in Asia and in the rainforests of the Americas, and consists mostly of aromatic trees. Being an essential oil producer, this family is used in the food, pharmaceutical, and cosmetic industries. This work presents a systematic review of the chemical composition and bioactivity of the essential oils from the Lauraceae family.

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Article Synopsis
  • Diplodia pinea was tested for its ability to inhibit the growth of several fungi, including Armillaria sp. and Botrytis cinerea, using a method where two fungi strains are grown together.
  • The study found that D. pinea significantly inhibited the growth of all tested fungi, showing a range of 30.75% to 98.37% inhibition and a moderate antagonist activity index of 14.5.
  • Chemical analysis identified certain compounds in D. pinea, such as steroids and phenolic compounds, which likely contribute to its ability to compete for resources with other fungi.
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Background: Plants and their parts are a part of life in many Brazilian communities, as observed in the jackfruit. The jackfruit seeds are consumed, usually, as roasted, boiled, steamed, and are eaten as a snack.

Objective: The present study was carried out to identify the seeds toxicity and cytotoxic activity.

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Article Synopsis
  • Dugesia tigrina, a non-parasitic flatworm, has been used in pharmacological studies due to its high sensitivity to drugs affecting the nervous system.
  • A study was conducted to evaluate the effectiveness of four Alzheimer’s medications (donepezil, tacrine, galantamine, rivastigmine) on inhibiting the enzyme acetylcholinesterase by testing five drug concentrations.
  • Galantamine demonstrated the strongest inhibitory effect, significantly reducing convulsant activity and locomotion in the planarians, indicating its potential for further research using this low-cost invertebrate model.
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Data on in vitro evaluation of extracts of three species of the Asteraceae family on the development of Trichostrongylidae eggs in sheep are presented. Egg hatchability was tested using herbal extracts prepared in a Soxhlet extractor, and using hydrolate prepared by means of hydrodistillation. The laboratory tests showed that the ethanol extract from flowers of the species Aster lanceolatus presented high activity against Trichostrongylidae eggs development in sheep, inhibiting larva formation by 91% within 48 hours, and maintaining similar rates after 72 hours.

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