High molecular weight adiponectin as a biomarker of hypertension in children and adolescents with obesity.

Lower HMW (high molecular weight) adiponectin levels are associated with obesity, insulin resistance, and metabolic syndrome in children and adolescents. However, data on HMW levels in pediatric population with hypertension are lacking. This study aimed to examine the association and predictive capacity of HMW levels, HMW/HOMA-IR, and HMW/APN ratio with hypertension in obese children and adolescents.

[The role of uric acid in the insulin resistance in children and adolescents with obesity].

Objective:: To investigate the association between serum uric acid levels and insulin resistance in children and adolescents with obesity.

Methods:: Cross-sectional study with 245 children and adolescents (134 obese and 111 controls), aged 8-18 years. The anthropometric variables (weight, height and waist circumference), blood pressure and biochemical parameters were collected.

Cardiac autonomic dysfunction in obese normotensive children and adolescents.

Objective: To test the hypothesis that obese normotensive children and adolescents present impaired cardiac autonomic control compared to non-obese normotensive ones.

Methods: For this cross-sectional study, 66 children and adolescents were divided into the following groups: Obese (n=31, 12±3 years old) and Non-Obese (n=35, 13±3 years old). Obesity was defined as body mass index greater than the 95th percentile for age and gender.