Muscle volume is related to trabecular and cortical bone architecture in typically developing children.

Introduction: Muscle is strongly related to cortical bone architecture in children; however, the relationship between muscle volume and trabecular bone architecture is poorly studied. The aim of this study was to determine if muscle volume is related to trabecular bone architecture in children and if the relationship is different than the relationship between muscle volume and cortical bone architecture.

Materials And Methods: Forty typically developing children (20 boys and 20 girls; 6 to 12y) were included in the study.

The pattern of trabecular bone microarchitecture in the distal femur of typically developing children and its effect on processing of magnetic resonance images.

Introduction: Magnetic resonance imaging (MRI) is used to assess trabecular bone microarchitecture in humans; however, image processing can be labor intensive and time consuming. One aim of this study was to determine the pattern of trabecular bone microarchitecture in the distal femur of typically developing children. A second aim was to determine the proportion and location of magnetic resonance images that need to be processed to yield representative estimates of trabecular bone microarchitecture.

Sex differences in trabecular bone microarchitecture are not detected in pre and early pubertal children using magnetic resonance imaging.

Introduction: Sex differences in trabecular bone microarchitecture have been reported in adults and adolescents, but studies in children are lacking. The primary aim of this study was to determine if there are sex differences in magnetic resonance imaging (MRI)-based measures of trabecular bone microarchitecture at the distal femur of children.

Materials And Methods: Pre and early pubertal boys (n=23) and girls (n=20) between the 5th and 95th percentiles for height, body mass and BMI were studied.