Publications by authors named "Joshua Richmond"
Background: Labyrinthine haemorrhage is a rare vascular disorder often presenting with the triad of acute vertigo, sudden sensorineural hearing loss and tinnitus. There are minimal reports on imaging progression over the acute period.
Index Case: A woman in her mid-40s presented with acute vertigo, sudden left-sided hearing loss and tinnitus, consistent with acute unilateral audiovestibular loss.
The adult zebrafish brain, unlike mammals, has a remarkable regenerative capacity. Although inflammation in part hinders regeneration in mammals, it is necessary for zebrafish brain repair. Microglia are resident brain immune cells that regulate the inflammatory response.
View Article and Find Full Text PDFAcute myeloid leukaemia (AML) is an aggressive haematological malignancy with poor prognosis. Increasing understanding of the molecular mechanisms driving clonal proliferation has resulted in advancements in classification and available therapeutic targets. Fms-related tyrosine kinase 3 (FLT3) mutations are prognostically important and offer options for targeted inhibition, however they are not stable and can emerge or disappear at relapse.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on treating acquired haemophilia A (AHA), a rare condition caused by autoantibodies against factor VIII, and examines management approaches in Queensland, Australia.
- A retrospective analysis of 24 diagnosed patients revealed a low incidence rate, with most patients being older adults; most initial bleeding events were not trauma-related, and rituximab was a common treatment option.
- Results indicated that low-dose rituximab was as effective as standard doses while achieving a high remission rate, suggesting it could be a preferred treatment strategy due to its favorable side effect profile.
Background: Reported US cases of chlamydia and gonorrhea have increased since 2000, whereas studies in select populations suggest that the prevalence of these diseases has decreased. We sought to determine if these diagnoses are increasing among pregnant women delivering at our center.
Methods: This is a retrospective study of women delivering at least 1 infant >18 weeks of gestation at the Medical University of South Carolina for 11 years (2008-2018).
Cancer treatment in the extreme elderly: case study of a 100-year-old lymphoma patient.
Int J Hematol Oncol
September 2016
Limited data are available on the treatment of older adults with cancer. Comorbidities may preclude the administration of effective therapies, particularly in the extreme elderly. Comprehensive geriatric assessment can identify specific weaknesses of the patient and predict unexpected toxicities, thus enabling an optimized treatment strategy in this population.
View Article and Find Full Text PDFObjective: To report a case of syndrome of inappropriate antidiuretic hormone secretion (SIADH) induced by a single oral dose of cyclophosphamide.
Case Summary: A 69-year-old woman was treated with oral CTD (cyclophosphamide/thalidomide/dexamethasone) chemotherapy for multiple myeloma. Two days after the first dose (including cyclophosphamide 500 mg), the patient developed vomiting, drowsiness, and headache.